[The flocculation-agglutination test in capillaries in the serologic diagnosis of typhoid fever in children].
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Biomedical subjects
Publications and source records attributed to M Ruiz-Castañeda.
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By means of the surface and color fixation test specific cross-reactions were detected in mixtures of serum from two patients suffering from the same type of neoplasia, and it was of interest that tests with 105 sera from well proven cases produced reactions which were consistent with the clinical and pathological reports.
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An attempt has been made to use the rapid surface fixation method for the investigation of immunological reactions in mixtures of sera from mothers and their mongoloid children. This preliminary report has been encouraging since all positive reactions were properly controlled with the serum of patients suffering from various clinical conditions but free of Down's syndrome. A water soluble substance was isolated from the urine of patients which produced positive reactions like those performed with the serum of mongoloid children.
Surface fixation has been used to detect antigen antibody-reactions with bacteria, protozooa and in some instances with drugs considered responsible of adverse reactions attributed to allergy. The application of this method to penicillin is reported. The test has been positive with serum from well-proven cases of hypersensitivity but also in subjects that had undergone penicillin treatment. So far, no comparative observations with conventional tests have been made; however, if the presence of circulating antibody is considered the cause of adverse reactions to penicillin, this simple test may have clinical usefulness.
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