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Biomedical subjects

M Runge

Publications and source records attributed to M Runge.

At least 73 records · Page 4Linked to original sources

[The functional dissociation of conduction within the human AV-node (author's transl)].

The functional dissociation (FD) of conduction within the AV-node is characterized by sudden prolongations and/or shortenings of the AH-time during stimulation. Examples for FD are presented during regular atrial stimulation and atrial extrastimulus technique. The appearance of FD is no proof for functional impairment of the AV-node. The blockade of the parasympathetic nervous system abolishes FD and leads to the well known continuous and regular adaptation of the AH-time with the various kinds of stimulation examined. It is recommended to replace the term "pathways" by the more comprehensive concept of functional dissociation with the AV-node.

Atrioventricular Node↗

Calcified remnants of the notochord in the roof of the nasopharynx.

Seven cases of calcification in the roof of the nasopharynx are reported. These calcifications situated in the midline opposite the pharyngeal bursa, were associated in four patients with a neural or osseous defect of the craniocervical junction. The authors estimate the frequency of this asymptomatic calcification to be about 0.1%. This finding is thought to be a calcified remnant of the notochord.

Brain↗

[Effect of aprindine in patients with normal and pre-damaged impulse forming and excitation conducting system/First communication; Sinus node function (author's transl)].

In 18 patients the influence of aprindine on sinus node function has been evaluated. The criteria were heart rate in spontaneous rhythm, sinus node recovery time (SRT), and the warm-up period after atrial stimulation with frequencies between 90 and 140/min. After aprindine the spontaneous rate increased significantly, whereas SRT and the warm-up period were not affected significantly. The patients with sinu-atrial disease showed a shortening of the spontaneous cycle-length and a decrease in SRT after aprindine. The results are discussed regarding the electrophysiological characteristics of the sinus node (slow current, automaticity) and their changes produced by stimulation and aprindine.

Aprindine↗

[Perforation of sinus of valsalva aneurysms (case report and review of the literature) (author's transl)].

A perforation in a case of sinus of Valsalva aneurysm misinterpreted first as perforated ulcer and later on as myocarditis made us review the literature (76 cases) for patients' history and diagnostic criteria which lead to the diagnosis. Special references were taken to the following subjects: localization of the aneurysms and direction of perforation; age and sex distribution at the time of perforation; ECG-changes and clinical symptomatology before and after perforation, and to diseases which must be taken into account for differential diagnosis.

Adult↗

[Clinical physiology and physiopathology of the atrioventricular node].

The functional behaviour of the healthy and sick human AV-node under various clinical-experimental conditions is described with special reference to (1) AV-nodal conduction, (2) AV-nodel refractoriness, (3) influence of autonomic tone and (4) role of the AV-node in the initiation of rhythm disturbances.

Adolescent↗

[Analysis of the stimulus formation and excitation conduction systems by electrostimulation and intracardiac registration of the ECG (author's transl)].

A program for investigating the stimulus forming and excitation conduction systems of the human heart by programmed stimulation and intracardiac lead, with its most important clinical indications, is presented. The parameters to be determined for function analysis of the individual structures, such as the corrected sinus node recovery time, conduction rates and functional and effective refractory periods are discussed with their electrophysiological principles and their clinical information value.

Bundle of His↗