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Biomedical subjects

M Rylski

Publications and source records attributed to M Rylski.

At least 19 recordsLinked to original sources
PubMed1995

[Diagnosis of Mycobacterium tuberculosis infections using PCR methods].

This study is the first application of molecular-genetic methods for diagnosis of Mycobacterium tuberculosis in Poland. Polymerase chain reaction (PCR) with primers targeted to insertion sequence-like element 6110 (IS6110) was used in the examination of sputum from 60 patients (30 with tuberculosis and 30 with other respiratory tract diseases). Results obtained by PCR were compared to microbiological methods (fast-acid staining, culture) and clinical examination. We found a 100% specificity of PCR.

Adult↗
PubMed1995

Environmental factors may regulate BCL2 associated lymphomagenesis: a very low incidence of BCL2-MBR translocation in Poland.

A characteristic feature of follicular non-Hodgkin's lymphomas (FL) is a chromosome translocation t(14;18)(q32;q21). In American patients the t(14;18) can be found in the large majority (approximately 70%) of FL and in a significant (10-40%) percentage of diffuse large cell lymphomas (DLCL). However there are reports suggesting that geographic or racial factors may regulate genesis of lymphomas with BCL2 abnormalities. Herein we present results of molecular analysis for t(14;18) in lymphomas in Poland. Analyses were performed on 37 cases of FL, 55 cases of diffuse lymphomas (DL) and 39 cases of Hodgkin's disease (HD). By Southern and polymerase chain reaction BCL2 translocation within major breakpoint region was found only in 3 of 37 FL, 1 of 55 DL and 2 of 39 HD. These results are the lowest reported ratio. We hypothesize that environmental factors may regulate BCL2 associated lymphomagenesis.

Base Sequence↗
PubMed1994

[Congenital peribronchial cyst of the right lung].

The authors present a case report of a congenital peribronchial cyst of the right lung producing pain. CT scan confirmed the above mentioned diagnosis. The patient was qualified for surgical removal of the cyst.

Bronchogenic Cyst↗
PubMed1993

[Aerobic and anaerobic bacterial flora as a cause of lower respiratory tract infection].

Bronchial aspirates collected from a group of 100 patients with respiratory infections undergoing broncho-fiberscopic examination have been tested bacteriologically. Twenty five patients was suffered from bronchopneumonia, 35 patients have had acute bronchitis, and 40 patients chronic bronchitis. Aerobic bacterial flora has been detected in 15% of patients, anaerobic flora in 13%, an mixed bacterial flora in 20%, totally in 48% of cases. Aerobic bacteria predominated in pneumonia. Bacteroides melaningogenicus prevailed in anaerobic flora. The tests of bacterial sensitivity to antibiotics have shown high sensitivity to cefotaxime, cefamandole, metronidazole, and rifampicin.

Bacteria, Aerobic↗