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M S Ansari

Publications and source records attributed to M S Ansari.

At least 55 records · Page 3Linked to original sources
PubMed2002

Diastereotopic effect in some N-substituted-3-methyl-4,1-benzoxazepine-2,5-diones.

1H NMR assignment of seven differently N-substituted-3-methyl-4,1-benzoxazepine-2,5-diones (I) revealed that with the exception of allyl, N-methylene protons of the substituents exhibit diastereotopy due to presence of a chiral centre in the heterocyclic ring at C-3. The significant finding is that the methylenes at C-2' in the substituents n-propyl and n-butyl (Id, Ie) also show diastereotopy. However, the one closer to the chiral centre (at C-1') exhibits greater non-equivalence of its protons. The diastereotopic methylene groups reported in this study correspond to the simplest system AB on one hand and as complex as ABMM'X2 or ABMM'X3 on the other. Calculated spectra obtained from assigned set of data for most of the coupled protons were in good agreement with the observed ones.

Magnetic Resonance Spectroscopy↗
PubMed2002

Recurrent adrenal pheochromocytoma: a case report.

We report an unusual case of benign recurrent pheochromocytoma that developed at the same site 8 years following initial treatment. This tumor was managed successfully through the 11th rib bed using the transperitoneal extrapleural approach.

Adrenal Gland Neoplasms↗
PubMed2002

Paradoxical incontinence caused by "invisible dysplastic" kidneys: role of laparoscopy.

A 35-year old female presented with paradoxical urinary incontinence. Examination under general anesthesia did not reveal any abnormality and cystoscopy showed absent right hemitrigone. Radiological and other renal imaging modalities revealed absent right kidney and normal functioning left kidney. Simultaneous localization and removal of small dysplastic right kidney was carried out by transperitoneal laparoscopy. Role of laparoscopy is emphasized in patients presenting with paradoxical urinary incontinence with no "visible" kidney/ureteric orifice on conventional evaluation.

Adult↗
PubMed2002

Chemoprevention of carcinoma prostate: a review.

PURPOSE: Chemoprevention of prostate cancer is the administration of agents to prevent, inhibit, or delay progression of prostate cancer. Opportunities exist for testing various types of chemopreventive interventsion. MATERIAL AND METHODS: The authors reviewed the relevant articles published in the last twenty years and studied the biology of the prostate cancer. An attempt is made to identify intermediate markers and surrogate endpoint markers. The various interventions and initial clinical trial results are described. End points for evaluation are mainly based on changes in PSA, changes of histological precursors, or time of onset of clinical disease. RESULTS: Nutritional factors such as reduced fat intake, vitamin A, vitamin E, vitamin C, vitamin D, Lycopene and selenium may have a protective effect against prostate cancer. CONCLUSION: Numerous studies implicate dietary and nutritional factors in the onset and progression of prostate cancer. Hence, it is possible that bioactive compounds (anti-oxidants) like vits. A, C, D, E, minerals like selenium and carotenoids like lycopene can be a part of chemopreventive strategies for prostate cancer. Ongoing studies on nutrition and prostate cancer may bring the required evidence to support what is still only a hypothesis at present. However, absolute recommendation will have to await the results of long term prospective clinical trials.

Animals↗
PubMed2002

Radiopaque shadow in the lumbar region on plain X-ray abdomen: diagnostic dilemma.

A 28-year-old man presented with right flank pain. Radiological investigations suggested the diagnosis of a calcified mass in the retroperitoneum below the right kidney. Laparoscopic exploration using the retroperitoneoscopic approach was performed. However, it was not possible to locate the lesion and an open exploration was done. During exploration a large fecolith was found trapped in a diverticulum of the cecum.

Adult↗
PubMed2002

Urethral recurrence after sigmoid orthotopic neobladder. What should be the ideal treatment approach?

Orthotopic neobladder reconstruction has become a standard procedure in patients undergoing radical cystectomy for invasive bladder cancer. In addition the known sequelae like nocturnal enuresis, need of self-intermittent catherisation and stricture at urethro or ureteroileal anastomosis, one of the most unfortunate event to happen is the recurrence of malignancy that may require the removal of the neobladder lessening the quality of life suddenly. There is a little information about the cases of urethral recurrence of transitional cell carcinoma of the bladder after cystectomy and orthotopic neobladder. We report such a case and management dilemma as the patient is young and does not want to loose body image and a brief review of literature is presented.

Adult↗
PubMed2002

Ectopic prostate: an unusual bladder tumor.

A 25-year-old man presented with gross painless hematuria. Cystoscopy revealed a smooth surfaced mass in the supratrigonal region. Complete transurethral resection of the mass was done. Histopathological examination revealed benign prostatic tissue situated ectopically.

Adult↗
PubMed2002

Holmium: YAG laser rescue for a stuck stone basket.

A 35-year-old man with left lower ureteric stone underwent ureteroscopic stone removal. Holmium: YAG laser lithotripsy was used to break the stone and to remove a larger fragment a 3 Fr. steel wire stone basket was introduced through the ureteroscope. However, during removal the basket with the stone became impacted in the intramural part of the ureter. All attempts to dislodge the stone and the basket failed. Laser fiber was introduced through the second channel of the ureteroscope bridge and the laser activated at settings of 0.5J and 10Hz. Pulverization of the stone did not free the basket and hence 2 wires of the stuck basket were cut with the laser. This enabled the basket to be freed and easily removed.

Adult↗
PubMed2002

Bilateral cryptorchidism with bilateral inguinal hernia and retrovesical mass in an infertile man: single-stage laparoscopic management.

A 30-year-old married man presented with the complaint of inability to procreate. Examination revealed bilateral nonpalpable testes and bilateral inguinal hernia. Ultrasonography of the abdomen could not locate the testis; instead, a hypoechoic 5 x 5-cm mass was found behind the bladder. A CT scan of the abdomen revealed the right testis near the right inguinal canal. The left testis could not be identified beside the soft tissue mass. The patient was taken for diagnostic as well as therapeutic laparoscopy. The testis on the right was found just proximal to the internal inguinal ring, and right orchidopexy was done. The left testis was small and rudimentary; hence, orchidectomy was done. Bilateral laparoscopic herniorrhaphy was carried out with polypropylene mesh by fixing it intracorporeally to the pubic bone, Cooper's ligament, inguinal ligament, and conjoint tendon. Subsequently, the retrovesical mass was excised and retrieved by dilating the umbilical port site. The operative time was 3.5 hours with minimal blood loss. The postoperative period was uneventful, and the patient was discharged after 24 hours. The histopathology examination of the retrovesical mass showed an extragonadal germ cell tumor compatible with seminoma.

Adult↗
PubMed2002

A rare case of urachovesical calculus: a diagnostic dilemma and endo-laparoscopic management.

Urachal anomaly in an adult is extremely rare, as the majority of urachal remnants obliterate shortly after birth. A 55-year-old man presented with irritative voiding symptoms. A plain film demonstrated a radiopaque shadow in the region of the urinary bladder. Ultrasonography showed a fixed echogenic focus in relation to the anterior bladder wall. With these investigations, the patient was referred to us with a diagnosis of a vesical stone. We suspected it to be a case of a urachal calculus. Therefore, a CT scan of the pelvis was obtained, which showed a midline tubular tract containing a cylindrical stone, further extending into the bladder as a pedunculated stone. The patient was managed by a combination of endoscopic and laparoscopic techniques. A urachovesical stone like a cherry (pedunculated) has not been reported previously in the English-language literature. This case also illustrates for the first time the combined use of endoscopy and laparoscopy to retrieve a urachovesical stone and the excision of the urachus.

Calculi↗
PubMed2002

Conservative management of spontaneous rupture of a sigmoid colon neobladder.

A case of successful management of spontaneous perforation of an orthotopic sigmoid colon neobladder 18 months following radical cystectomy for muscle-invasive transitional cell carcinoma is described. Conservative management of such perforations has rarely been described in the literature; however, this is the first case report of sigmoid colon neobladder perforation and of its successful conservative management, to the best of our knowledge.

Colon↗
PubMed2001

Impact of power index, hydroureteronephrosis, stone size, and composition on the efficacy of in situ boosted ESWL for primary proximal ureteral calculi.

OBJECTIVES: The efficacy, safety, feasibility, and outcome of in situ treatment applied to select proximal ureteral calculi was assessed and analyzed with a view to avoiding auxiliary interventions and providing high clearance rates in the shortest possible time. We studied the impact of several clinically important variables, including power index, degree of hydroureteronephrosis (HDUN), stone size, and composition on the efficacy of sequential in situ boosted extracorporeal shock wave lithotripsy (ESWL) in a select group. The power index requirement for the in situ boosted protocol and the impact of the stone size/composition, degree of HDUN, and clearance rates were also analyzed. METHODS: An in situ (no instrumentation) boosted protocol was applied to 130 primary unimpacted proximal ureteral calculi with no prior intervention. A typical session with the Siemens Lithostar Plus comprised 3000 shock waves, in installments of 500, deployed at a power setting of 1 to 4 kV with a gradual stepwise escalation. Sequential boosted additional sessions of ESWL were administered on days 2, 7, and 14, tailored to the degree of fragmentation, clearance status, and amount of residual stone bulk. Several parameters (shock waves, kilovolts used, fluoroscopy time, number of sessions, stone size, composition, fragmentation, clearance, and HDUN) were recorded and the results analyzed statistically. RESULTS: The results were excellent in 83.8%, with a mean duration to complete clearance of 11.3 days. In situ ESWL failed in 7.69%, and the auxiliary intervention rate was 10.7%. Pre-ESWL HDUN was present in 78.3%, the mean power index was 184.6/session/case, and the average stone burden was 8.9 mm(2). Calcium oxalate monohydrate was the most common stone (56%). Renal colic was the most common side effect observed. The power index, fragmentation at the first session, and stone size were found to be the most favorable significant variables affecting stone clearance. The degree of HDUN, number of sessions, and stone composition did not significantly impact the clearance rates. CONCLUSIONS: In situ boosted ESWL should be the first-line therapeutic modality in select unimpacted primary proximal ureteral stones.

Adolescent↗
PubMed2001

Malignant paraganglioma of the urinary bladder. A case report.

Paraganglioma (pheochromocytoma) is probably the most fascinating of all tumors as it can present with a wide range of clinical manifestations. Paraganglioma of the urinary bladder is one of the rare tumors and constitute less than 10% of all bladder tumors. The common presentation of paraganglioma of the urinary bladder is painless haematuria, headache, palpitation and anxiety. Malignancy is uncommon and no histological feature is characteristic of malignancy. Invasion of adjacent organs or metastasis to the lymph nodes is the only criteria to suggest malignancy. In the presence of proven metastasis radical cystectomy with pelvic lymphadenectomy is recommended. In the present case the tumor was arising from anterior wall of the bladder away from the bladder neck and that in a large capacity bladder it was possible to get a wide margin for partial cystectomy along with bilateral pelvic lymphadenectomy without violating the oncological principles. At a follow up of two years there is no evidence of recurrence of tumor.

Adolescent↗
PubMed2001

Laser endoscopic incision: a viable alternative to treat adult ureterocele.

AIM: To prospectively evaluate the safety. efficacy, feasibility and outcome of Nd-Yag laser endoscopic incision in adult symptomatic patients with intravesical uretroceles. METHODS: We present our experience with the use of Nd-Yag laser for endoscopic incision of the adult ureterocele in a group of five symptomatic adult patients. RESULTS: All the five patients showed excellent decompression with relief from flank pain and hydronephrosis and none demonstrated a post-op vesicoureteric reflux (VUR). CONCLUSION: Laser endoscopic management of intravesical ureteroceles is new emerging modality, which is being increasingly employed to decompress ureteroceles. Laser endoscopic incision is a precise and bloodless procedure enabling a clean accurate controlled cut through the endoscope as opposed to the traditional bugbee electrode.

Adult↗
PubMed2001

Colovesical fistula an unusual complication of cytotoxic therapy in a case of non-Hodgkin's lymphoma.

A 65-year old man, a known case of non-Hodgkin's lymphoma of base of the tongue and epiglottis presented with complaints of pneumaturia and faecaluria. He had received the first cycle of cytotoxic therapy (CHOP-regimen). At the end of the cycle he developed febrile neutropenia (circulating granulocyte count <1500/mm3). Cystogram showed air in the bladder area and a fistulous communication to a cavity behind the bladder. CT-scan showed air in the bladder, a fistulous communication between the sigmoid colon and bladder along with an intervening small abscess cavity. On exploration a fistulous communication between the sigmoid and bladder along with an intervening small abscess cavity was found. Resection of involved portion of sigmoid and end to end anastomosis along with a diverting colostomy was done. The bladder was closed in two layers with an omental interposition between it and the sigmoid along with a suprapubic cystostomy. The histopathology demonstrated only inflammatory response without any evidence of malignancy or diverticular disease.

Aged↗