[Risk factors of mortality in critically ill patients with thrombocytopenia].
OBJECTIVE: Determine predictive factors of intensive care mortality in thrombocytopenic patients. STUDY DESIGN: Retrospective study. PATIENTS AND METHODS: Data including the last 100 patients hospitalised in intensive care unit during period from March 2002 to January 2003 and having presented, at least one time, a platelet count <150 x 10(9)/l. Comparison between patients was realized according to the definitive issue (death or discharge from intensive care). RESULTS: Incidence of thrombocytopenia was 27%. Mortality rate was 53%. Thrombocytopenia in admission was noted in 44% of the patients. IGS II score (OR = 1.05 and p = 0.014), sepsis (OR = 34.2 and p = 0.002) or hepatic dysfunction cases (OR = 42.5 and p = 0.026) were predictive factors of death in intensive care unit when thrombocytopenia occurred. CONCLUSION: Our results concerning prognostic value of thrombocytopenia in intensive care unit are partly similar to those of literature with a surmortality associated to thrombocytopenia related to sepsis and hepatic dysfunction.