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Biomedical subjects

M S Grewal

Publications and source records attributed to M S Grewal.

At least 19 recordsLinked to original sources
PubMed1991

Cardiovascular effects of nasotracheal intubation.

Intubation time, arterial pressure, heart rate and arterial oxygen saturation during nasotracheal intubation effected with the Macintosh laryngoscope blade were compared with those during orotracheal intubation. The 60 patients studied received a standardised general anaesthetic and were randomly allocated to one of two groups immediately before tracheal intubation. The mean nasal intubation time (33.2 seconds) was significantly greater than mean oral intubation time (14.8 seconds). The mean arterial pressure changes in the nasal group were significantly greater and more prolonged than in the oral group. The mean heart rate in the nasal group was significantly lower than in the oral group during the first minute after intubation, after which heart rates were similar. There were no significant differences between the two groups with regard to arterial oxygen saturation levels at any stage.

Adolescent↗
PubMed1987

Genetic appraisal of congenital cataract.

A total of 45 congenital cataract cases were studied for chromosomal aberrations and dermatoglyphic patterns. Whereas parents showed no marked differences, patients showed marked differences in different dermatoglyphic traits as compared to age-sex matched controls. Out of all the patients Rubella, hereditary and undetected actiology groups showed variations differently, SCE were seen in all cataracts irrespective of their aetiology as compared to controls.

Cataract↗
PubMed1983

DNA loss in the developing cerebellum of nervous mouse: a flow cytometric study.

Flow-cytometry of cerebellar EGL cells of nervous (nr) mouse revealed a reduction in DNA quantity per cell accompanied by an increase in the DNA dispersion during 6-8 days of postnatal life. This loss of DNA is due to a partial degeneration of the cells of EGL during the first week of postnatal life. The surviving cells later on achieve a DNA content equivalent to their bone marrow cells. The flow-cytometric technique also facilitates an early detection of the homozygous nervous mutant, almost 2 weeks before the clinical manifestation of the disease, which to date was not possible.

Animals↗
PubMed1980

Effect of natural background radiation on dermatoglyphic traits.

Long term exposure to natural background radiation could cause gross abnormalities in individuals and at the population level. Studies conducted on the coastal Kerala population which is known to be receiving fifteen times the normal permissible dose of radiation support this. This study aims at understanding the deviations, if any, in the normal human variation as a result of such high natural radiation. A detailed quantitative and qualitative dermatoglyphic study was done on two communities i.e. Hindus and Christians, living separately in the radiation area. The significant differences were observed between control and exposed groups with regard to d-t ridge count, distances c-t and angle atd. The susceptibility of the axial triradius to environmental distrubances is discussed.

Background Radiation↗
PubMed1980

Birth weight and development of cerebellar cortex.

Postnatal development of the cerebellar cortex in the mouse is characterised by proliferation of cells of the external granular cell layer, migration of the granule cells across the molecular layer and simultaneous maturation of the Purkinje cells. At the same time, there is elaboration of the folia and fissures of the cerebellum. These features were studied postnatally in relation to the age and weight of the animal in the inbred strain of C3HeB/FeJ mice fed on standard diet. In every litter there was a difference in body weight of the various pups, and for the present study, the lowest and highest weighing animals from each litter were used. The observations presented here are on animals at the 1st, 7th, 13th and 24th days postnatum. It appears that the size of the cerebellum and the degree of the development of the cerebellar cortex are directly proportional to the weight of the animal for that age period.

Aging↗