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Biomedical subjects

M S Hendy

Publications and source records attributed to M S Hendy.

13 recordsLinked to original sources

Recurrent embolotherapy in Dieulafoy's disease of the bronchus.

Dieulafoy's disease is a vascular anomaly characterized by the presence of a dysplastic artery that is related to an epithelial ulcer. The French surgeon Georges Dieulafoy first described it in 1898. Most frequently, it is a gastrointestinal condition, but occurrence in the bronchus has been reported in a few cases. The case of a 52-year-old man with massive hemoptysis, for which he underwent successful embolotherapy 10 years previously, is described. Over the next 10 years, he had several hospital admissions due to hemoptysis, and he underwent successful embolotherapy on each occasion. This case report underlines the importance of bronchial arteriography as the investigation of choice for massive hemoptysis.

Adult↗

Effect of ketotifen on the bronchodilating action of aminophylline.

The use of methyl xanthine derivatives for the treatment of bronchospasm is limited by unwanted side-effects which are frequently dose related. Potentiation of the bronchodilating effects of these derivatives would therefore have obvious clinical advantages. This paper reports the results of a trial designed to elucidate whether potentiation occurs between aminophylline and ketotifen.

Adolescent↗

The effects of naloxone infusion and stellate ganglion blockade on hot flushes in the human male.

A 77-yr-old man presented with severe episodes of hypotension, flushing and sweating starting immediately after infarcting his only remaining functioning testis. The attacks were shown to be mediated by the cervical sympathetic chain, the reaction on the face and neck being abolished by a stellate ganglion block. The severity and frequency of sweating was also considerably reduced with naloxone as may be seen in female climacteric flushing. Injection of testosterone significantly reduced the frequency and severity of the attacks, which were unaltered by oestrogen treatment.

Aged↗

Occupational asthma due to an emulsified oil mist.

A toolsetter developed occupational asthma due to the oil mist generated by his lathe on which it was used as a coolant. The diagnosis was confirmed by serial measurements of peak expiratory flow at home and work, including a prolonged period away from work. Occupational type bronchial provocation tests were performed using the whole emulsified oil and its components separately. He reacted specifically to the whole emulsified oil and to the reodorant, a pine oil preparation. He also reacted to colophony, a constituent of the emulsifier.

Asthma↗

Captopril-induced acute renal artery thrombosis and persistent anuria in a patient with documented pre-existing renal artery stenosis and renal failure.

We describe an elderly man, with pre-existing renal failure and atheromatous renal artery stenosis, who developed persistent anuria due to renal artery thrombosis after acute hypotension following captopril administration. Caution should be used when captopril is first administered to patients with impaired renal function in whom renal artery stenosis is known or suspected.

Aged↗

The influence of transbronchial lung biopsy and bronchoalveolar lavage on arterial blood gas changes occurring in patients with diffuse interstitial lung disease.

Serial arterial blood gases were measured during fibreoptic bronchoscopy in 26 patients with diffuse interstitial lung disease. All those having transbronchial biopsy with or without bronchoalveolar lavage, performed breathing room air, showed significant falls in PaO2, at the time of passage of the bronchoscope through the vocal cords both at the beginning and end of the procedure. Patients having bronchoalveolar lavage and transbronchial biopsy performed with supplementary oxygen at least maintained their basal PaO2 levels. Cessation of the supplementary oxygen 30 minutes after withdrawal of the bronchoscope did not result in rebound hypoxaemia. Bronchoalveolar lavage and transbronchial biopsy can be performed safely in patients with diffuse interstitial lung disease without significant hypoxaemia developing, if oxygen is started before the procedure and continued for 30 minutes after withdrawal of the bronchoscope.

Adult↗