Biomedical subjects
Publications and source records attributed to M S Hnatiuk.
In experiment on white rats was evaluated the positive effect of food deprivation on heart damaged by norephynephrine. Magneto-laser irradiation increased the adaptive resources of cardiovascular system during food deprivation and norephynephrine myocardiodystrophy.
The local immune homeostasis changed of the colon play a significant role in the pathogenesis of toxic colitis, induced by lead acetate. Chronic toxic colitis is accompanied by a considerable redistribution of plasmocytes-producers of the main immunoglobulins classes in the colon walls towards a primary IgA producers increase, a correlation between them and the local immune reactions tension and destabilization as well. Enterosorbent SCNP-2 influence on a pathological process in the colon under the chronic lead intoxication results in the local immune reactions improvement in the studied organ, its functional and structural elements impairment rate reduction as well as their adaptive properties increase.
Among the investigated 27 gallbladders (GB) using immunofluorescent and histological methods 9 were nonaffected, 7--excised for an acute calculous cholecystitis and 11--for the destructive one. It was established, that the plasmocytes, producing immunoglobulins of main classes, play an important role in the immune defense of the GB mucosa. The stress and hyperfunctioning of the local immune homeostasis mechanisms were revealed in the acute calculous cholecystitis; in the destructive one--the local immune defense disorder, showing the essential lowering of the secretory immunoglobulin A (SIgA) level and the immunocytes-producers IgA quantity, the ratio between plasmocytes and immune complexes, which appear in the vessels wall and perivasal stroma of GB.
By means of ultrastructural and morphometrical methods hearts of 15 white rats have been studied during adaptation to the physical static load. This exercise induced the adaptive changes of the myocardium: hypertrophy and dilatation of the heart chambers. Hypertrophy of the myocardial parts takes place mainly at the expense of increasing of the length and width of cardiomyocytes. In these structures the increase of synthetic and secretive function was founded. Moderate training have improved the metabolism of the cardiomyocytes and created certain reserve of energy in the structures which were connected with the process of adaptation after the physical static load.