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Biomedical subjects

M S Huckman

Publications and source records attributed to M S Huckman.

At least 55 records · Page 3Linked to original sources

Radiology of suprasellar ectopic pinealoma.

The radiographic and clinical findings in twenty-three recently reported cases of suprasellar ectopic pinealoma are reviewed and three previously unreported cases are described. It is concluded that suprasellar calcification is extremely rare; enlargement of the sella turcica was present in approximately 20 to 30 per cent, none demonstrated elevation of the anterior cerebral artery. Pneumography may show a smooth or irregular filling defect in the anterior part of the third ventricle. In one of the new cases there was an isotope uptake in the suprasellar region. The differential diagnosis and other clinical data are also discussed.

Adolescent↗

Dementia in the elderly--a search for treatable illnesses.

Forty patients with senile dementia were evaluated prospectively with laboratory and radiologic investigations, including computerized axial transverse tomography. Five patients were believed to have potentially treatable illnesses causing the dementia. After treatment, the dementia in one patient with hypothyroidism was completely resolved. One patient with pernicious anemia was markedly improved, and a second patient with hypothyroidism was somewhat improved. One patient with a brain tumor was not treated, and a severely demented patient with possible normal pressure hydrocephalus died shortly after shunting without improvement. The discovery of these unsuspected illnesses and the gratifying response to treatment in some suggests the importance of systematic evaluation in all patients with senile dementia.

Aged↗

Use of computerized tomography in senile dementia.

Computerized tomography was used to evaluate 35 patients with senile dementia and proved to be a simple and practical screening procedure. Those patients with moderate or severe cerebral atrophy had a poorer short-term prognosis than those with questionable or mild atrophy. Two patients with potentially treatable illnesses (hypothyroidism and pernicious anaemia) and only questionable atrophy had reversal of the dementia with treatment. A single patient with moderate atrophy had a potentially treatable illness (hypothyroidism) which only partially resolved. Those patients with dementia but relatively little atrophy by computerized tomography may represent a unique group with a better prognosis who require particularly careful evaluation for potentially treatable illnesses.

Aged↗

The validity of criteria for the evaluation of cerebral atrophy by computed tomography.

Computed tomography of the brain was used in evaluating demented and nondemented elderly people. The incidence of convulutional atrophy and ventricular enlargement correlated well with pathologic and pneumoencephalographic examination of a similar population. Computed tomography also showed certain instances of dementia without atrophy and evidence of atrophy without dementia. The absence of brain atrophy in a demented patient should prompt a search for a potentially treatable cause of the dementia. The authors discuss criteria for diagnosing atrophy by computed tomography and conclude that, because of its noninvasive nature, it is a valuable aid in screening demented patients for treatable diseases.

Aged↗

Clinical experience with the intravenous infusion of iodinated contrast material as an adjunct to computed tomography.

The intravenous infusion of iodinated contrast material is an important adjunct to computed tomography with a wide variety of lesions. Some arteriovenous malformations, metastatic lesions and tumors of the sella turcica and cerebellopontine angle which are undetectable by conventional computed tomography may be visualized by this method. Certain other metastatic lesions, primary tumors, abscesses and infarcts which are detectable in the preinfusion tomogram become better defined following infusion. The indications for this examination and the procedures involved are discussed.

Astrocytoma↗

Temporal arteriography. Analysis of 21 cases and a review of the literature.

To define the role of temporal arteriography in the diagnosis of giant-cell arteritis, the results of temporal arteriography in 21 patients who had temporal artery biopsies were reviewed. Abnormal angiography was found in all patients with biopsy-proven giant-cell arteritis, in some patients with polymyalgia rheumatica and normal biopsy, and in some patients with neither polymyalgia rheumatica nor giant-cell arteritis. No pattern of angiographic abnormality typical for giant-cell arteritis could be found. Results suggest temporal arteriography is a sensitive but nonspecific procedure in the diagnosis of giant-cell arteritis and must be coupled with biopsy of angiographic abnormalities for confirmation of diagnosis.

Giant Cell Arteritis↗

The magnetic resonance hypointense spine of AIDS.

The T1-weighted magnetic resonance examinations in 11 acquired immunodeficiency syndrome patients showed substantial reduction in signal intensity of vertebral bodies. Review of bone marrow aspirates and biopsies that were available in eight patients suggested that the abnormality resulted from markedly increased amounts of storage iron within the bone marrow, probably secondary to the anemia of chronic disease.

Acquired Immunodeficiency Syndrome↗

Chemonucleation and changes observed on lumbar MR scan: preliminary report.

This study examines the relation between the postchemonucleation clinical outcome and changes observed on the lumbar MR scan. Eight of 12 chemonucleated disks showed clinical improvement at the last follow-up, while the other four showed no improvement. In the cases that showed improvement there was a decrease in one or both dimensions of the defect in the thecal sac. Seven of eight showed an increase in the peridisk signal. Where there was no clinical improvement there were fewer decreases in the size of the defect, and three of four showed no increase in the peridisk signal.

Adolescent↗