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Biomedical subjects

M S Jaffe

Publications and source records attributed to M S Jaffe.

At least 19 recordsLinked to original sources

Intrathecal baclofen for generalized dystonia: a case report.

Dystonia is an abnormal movement characterized by sustained muscle contractions, frequently causing twisting and repetitive movements or abnormal postures. Primary generalized dystonia usually evolves to a debilitating condition, often unresponsive to oral pharmacologic regimens or physical rehabilitation. We present the case of a patient with idiopathic adult-onset generalized dystonia who was recalcitrant to oral therapies. This patient was treated with intrathecal baclofen therapy and responded dramatically with improved functional abilities, resolution of chronic pain, and an improved rating on the dystonia scale.

Aged↗

A population-based survey of in-line skaters' injuries and skating practices.

OBJECTIVE: To describe in-line skating interests and practices, protective gear usage, and injury patterns in a population-based group of in-line skaters. DESIGN: A two-page questionnaire with multiple choice questions and one write-in response question. PARTICIPANTS: The survey was sent to 1,000 members of an in-line skating club in Detroit, MI and 45 other states. MAIN OUTCOME MEASURES: The study was designed to profile skater injury patterns. The effects of protective gear and skater lessons on injury were examined. RESULTS: Of the 435 skaters returning questionnaires, 56.7% were men. The mean age was 35 years. The frequency of in-line skating lessons was 31.7%. Of respondents, 72.5% wear some kind of protective gear while skating, and 79.8% reported that they had been injured while skating. Of those who had skated for 5 or more years, 93.7% had been injured. Upper extremity injuries were reported by 58.8% of skaters and lower extremity injuries by 66.7%. The majority suffered abrasions and bruises only. More serious injuries were reported by very few skaters: fractures by 5.5% and concussions by 2.1%. Only 3% of respondents required orthopedic surgery. CONCLUSION: Lessons and protective gear decrease the risk of injury. However, risk of incurring minor injury exists even if full protective gear is used. Those who have skated for more than 5 years are almost certain to report having been injured.

Adolescent↗

Interactions of age, ear, and stimulus complexity on dichotic digit recognition.

The effect that the aging process has on recognition performance was studied using a hierarchy of 1-pair, 2-pair, 3-pair, and 4-pair dichotic digits (1, 2, 3, 4, 5, 6, 8, 9, and 10, male speaker). Two groups of right-handed subjects were studied: 20 adults < 30 years of age with normal hearing and 20 adults 60-75 years with mild-to-moderate hearing loss. Each of the multipaired sets contained the 72 possible 1-pair digit combinations in each presentation position with no digits repeated in a set. A three-way analysis of variance with repeated measures indicated three significant differences. First, as the complexity of the listening task increased from 1 pair to 2 pairs to 3 pairs to 4 pairs, recognition performance decreased systematically and significantly. The decreases in performance between the 1- and 4-paired conditions were larger for the left ear than for the right ear and were larger for the 60-75 years group than for the < 30 years group. Second, performance on the materials presented to the right ear was significantly better than performance on the materials presented to the left ear. Third, recognition performance by the < 30 years group was significantly better than recognition performance by the 60-75 years group. Recognition performance on the 1-pair condition was near maximum for both subject groups. Between the 1- and 4-paired conditions, recognition performance for materials presented to the left and right ears decreased 15.7 percent and 10.0 percent, respectively, in the < 30 years group and decreased 29.3 percent and 15.7 percent, respectively, in the 60-75 years group.

Adult↗

Glare disability in eyes with intraocular lenses.

For 32 eyes tested for glare disability after undergoing extracapsular cataract extraction with implantation of posterior chamber intraocular lenses, the mean contrast threshold in the presence of the glare source was 23% for undilated pupils and 31% with dilation. A regression analysis of glare scores as a function of the amount of posterior capsule opacification showed a significant (P less than .00001) association between the two.

Aged↗

Retinal detachment in myopic eyes after intracapsular and extracapsular cataract extraction.

We analyzed two consecutive series of cataract extractions in patients with moderate to severe myopia for the incidence of postoperative retinal detachment. One series consisted of 122 intracapsular cataract extractions without surgical loss of vitreous and the other series consisted of 151 extracapsular (phacoemulsification and planned extracapsular) cataract extractions without loss of vitreous and with intact posterior capsules. All patients were 40 years of age or older and all were followed up for one to four years. We defined moderate to severe myopia as an aphakic refraction of +7.00 diopters spherical equivalent or less. The rate of postoperative retinal detachment was greater in the intracapsular series (seven of 122 cases; 5.74%) than in the extracapsular series (one of 151 cases; 0.66%).

Adult↗

Bilateral intraocular lens implantation.

A study of 1796 consecutive cataract patients in a posterior chamber intraocular lens implant (IOL) series revealed 373 patients (20.8%) who had bilateral IOLs. Visual acuity was 20/40 or better in 87% of first eyes operated and 90% in second eyes. The major cause of vision less than 20/40 was senile macular choroidal degeneration in both first and second eyes. The surgical reintervention rate was 11.8% in first eyes and 3.7% in second eyes. Ninety-two percent of patients had an interval of six months or more between surgery on the first and second eyes.

Cataract Extraction↗

A comparison of ICCE-Binkhorst intraocular lens and ECCE-posterior chamber intraocular lens, thirty-four to forty months postoperatively.

A retrospective study of 450 consecutive intracapsular cataract extractions with a Binkhorst lens implant, and 450 consecutive extracapsular cataract extractions with a posterior chamber lens implant, was performed. All patients were examined between 34 and 40 months postoperatively, except for those patients who died before this time, those lost to followup, or those who were otherwise unavailable during this time. The results suggest that the extracapsular series had a more favorable outcome than the intracapsular series, especially with regard to final visual acuity and the incidence of clinical cystoid macular edema.

Cataract Extraction↗

Cystoid macular edema after intracapsular and extracapsular cataract extraction with and without an intraocular lens.

A prospective cystoid macular edema study of aphakic and pseudophakic patients showed that extracapsular cataract surgery has a lower rate than intracapsular surgery when the surgery is uncomplicated. There was no difference in the rates with intracapsular surgery with and without an intraocular lens. A complicated extracapsular with an intraocular lens has a higher rate than when the surgery is uncomplicated. In extracapsular surgery with complications, there is no difference in the rates with and without an intraocular lens. When complications occur, the ratio of clinical to angiographic-proven cases is higher than when the surgery is uncomplicated. This study included four series of uncomplicated cataract extractions and three series of complicated cataract extractions. A fluorescein angiogram was performed on every patient at least one year after surgery.

Cataract Extraction↗

The results of extracapsular cataract extraction with a Shearing posterior chamber lens implant 34 to 40 months after surgery.

A series of 300 consecutive extracapsular cataract extractions with a Shearing posterior chamber lens implant (plus 13 with a surgical complication necessitating another kind of lens implant or no implant) was evaluated 34 to 40 months after surgery, except for those who died before this time (21 patients) and those lost to follow-up (15 patients). Ninety-one percent of the 264 patients who were examined achieved 20/40 or better visual acuity. Ninety-one percent of the 300 patients (those examined plus those who died and those lost to follow-up according to their last recorded examination) achieved 20/40 or better visual acuity. This series was compared to a previously reported series of 300 consecutive intracapsular cataract extractions with a Binkhorst iris clip lens implant examined 34 to 40 months after surgery.

Aged↗

Intraocular lenses, axial length, and retinal detachment.

A large series of patients with intraocular lens implants had an overall 0.98% incidence of retinal detachment (eight detachments in 819 eyes). Within this group, patients with axial lengths of more than 25 mm had a statistically significantly higher incidence of retinal detachment (P = .054).

Aged↗

The results of intracapsular cataract extraction with a Binkhorst iris clip lens implant 34 to 40 months after surgery.

A series of 300 consecutive intracapsular cataract extractions with a Binkhorst iris clip lens implant was evaluated 34 to 40 months after surgery, except for those patients who died before this time (30 patients) and those lost to follow-up (13 patients). Eighty-eight percent of the 257 patients achieved 20/40 or better visual acuity. The results were similar to those series previously reported by the authors where the final examination time for each patient was not uniform.

Aged↗

Digital mucinous pseudocysts.

Thirty-one patients with 46 digital mucinous pseudocysts are reviewed. The pseudocysts are usually soft, fluctuant, dome-shaped, dimpled, smooth lesions located near and often associated with a linear defect of the fingernail. Transillumination confirms the diagnosis. Treatment is conservative, usually consisting of intralesional injections. If surgery is necessary, distal interphalangeal joint injection of methylene blue aids in complete removal by identifying the mesothelial-lined pedicle leading from the distal joint to the pseudocyst.

Adult↗

Retinoblastoma simulating Coats' disease: a clinicopathologic report.

A case report of a male infant with leukocoria and a clinical picture of Coats' disease is presented. The correct diagnosis was suggested by contact B-scan ultrasonography, which demonstrated an exophytic mass with calcification compatible with retinoblastoma. The value of this technique in the differential diagnosis of retinoblastoma is discussed.

Child, Preschool↗