The use of 5-fluorouracil cream to define suitable donor areas.
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Biomedical subjects
Publications and source records attributed to M S Litwin.
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Stored human whole blood and red blood cells of varying age were passed through dual mode microscope blood transfusion filters. Passage through the filters resulted in markedly decreased screen filtration pressure (SFP) of the blood and increased filter weights. Numerous microaggregates were removed and SFP returned to normal. Filtration resulted in reduced platelet and white cell counts but other blood components were not adversely affected. On the basis of this research, we conclude that this micropore blood transfusion filter is effective in removing microaggregates from stored whole blood and red blood cells. It has a high capacity and rapid flow rate and is reliable during pressure transfusion.
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Trauma causes a definite increase in packed cell viscosity and intravascular cellular aggregation. As a result, total body oxygen consumption decreases markedly. When packed cell viscosity is lowered by infusion of dextran-40, total body oxygen consumption progressively increases to normal values. It does not appear unreasonable to conclude that in traumatized patients, restoration of microcirculatory blood flow is of great importance in reestablishing an effective circulating blood volume and that normalization of blood viscosity after trauma may be of considerable benefit.
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