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Biomedical subjects

M S Liubarskiĭ

Publications and source records attributed to M S Liubarskiĭ.

At least 19 recordsLinked to original sources
PubMed2002

[Morphologic aspects of transplantation of vascularized tissues complexes].

Microcirculation and tissue leukocytes in transplanted on vascular peduncle tissue complex were studied with light microscopy. Lymph outflow disorders were the causes of transplant edema. Lymph outflow and hemocirculation were restored through new vessels formation that was revealed in all transplant tissues over 2-8 months after transplantation. With time, processes of sclerotic transformation in tissues of transplanted flap progress due to denervation and function loss of transplanted tissues.

Adolescent↗
PubMed2002

[Adsorption therapy for acute suppurative periostitis of the jaw].

Capillaries and tissue leukocyte cytograms in soft gingival tissues were examined by optic microscopy in patients with acute purulent periostitis of the jaws treated by different methods. Disorders in the lymph outflow from gingival tissues were detected, which were due to dilatation of the lymph vessels and interstitial spaces in the mucosal lamina propria and stasis with leukocyte aggregation and purulent clots in the lumina of many lymph vessels. Less pronounced dilatation of interstitial spaces and lymph vessels, higher counts of lymphocytes, monocytes, and macrophages in the tissues of the gingival mucosa lamina propria, observed 2 days after the beginning of adsorption therapy of the subperiosteal abscess cavity, indicate that this therapy is more effective in acute purulent periostitis than traditional treatment.

Acute Disease↗
PubMed2001

[Effects of the enterosorbent SUMS-1 on isoniazid pharmacokinetics and lipid peroxidation in patients with pulmonary tuberculosis and drug-induced hepatic lesions].

The use of the enterosorbent SUMS-1 in the combined therapy for pulmonary tuberculosis patients with drug-induced toxic hepatic lesion arrests the clinical and laboratory manifestations of endotoxicosis, removes antibiotic intolerance, increases the elimination rate of isoniazid, and reduces its distribution scope, the area beneath the kinetic curve being unchanged. The plasma concentrations of primary products and after-products of lipid peroxidation products during enterosorbent therapy decline and the levels of ceruloplasmin and alpha-tocopherol remain unchanged.

Adult↗
PubMed2000

[Morphological changes of lymphatic system in patients with the lymphedema of lower extremities].

Morphological changes in inguinal lymph nodes, lymphatic collector and subcutaneous space were studied up in patients with the lower extremities lymphoedema. While the lower extremities lymphoedema occurs in inguinal lymph nodes the connective tissues spreading in two variants is observed. In the first one fibroblasts and collagen fibres appears in medullar substance (chordae medullaris and medullar sinuses) and in the second the sclerosis process begins from cortical plateau and paracortical zone. It is expedient to include the intraarterial infusion of the xenospleen preparations in complex of treatment of patients with initial stage of the lower extremities lymphoedema, especially in the absence of possibility to proceed with microsurgical intervention and the erysipelas presence in anamnesis.

Adolescent↗
PubMed1999

[The artificial lymph node].

Adsorption of lymphocytes on the sorbents in correction of inflammatory lesions has significant clinical perspectives as the cells and active biological substances they secrete function actively in inflamed tissues acting in the site of its application: every cell adsorbs and inactivates foreign substances, every cytokin affects certain target cells. The products of these cells functioning and dissociation as well as the products of immune system reaction to them remain on the sorbent and are eliminated together with granules during bandaging or by the end of the treatment thus do not entering the organism. Lymphocytic monolayer on the sorbent does not prevent its specific action in pathologic nidus. In this case sorbent does not only drain the tissue duplicating certain primitive non specific functions of regional lymph node (barrier, filtrating, transport, draining and protective functions) but also performs certain highly specialized functions of immunocompetent organs--selective adsorption and inactivation of antigenic substances. It is reasonable to use sorbents for adsorbing lymphocytes in kapron containers which exclude the preparation leak into wounds and cavities and act as a filter preventing fast inactivation of the preparation by large fragments of tissue detritus.

Animals↗
PubMed1992

[Possibilities of restoration of the regional lymphatic channel by the use of sorbents in the treatment of experimental generalized purulent peritonitis].

Regional lymphatic bed in local application of mineral sorbent SUMS-2p in 80 white noninbred rats with experimental generalized purulent peritonitis is studied with the use of indirect intravital lympho-roentgenography. The correlation between lympho-dynamics and generalized purulent peritonitis stage was observed. It is shown that the peritoneo-sorption with the mineral sorbent SUMS-2p led to early restoration of lympho-drainage.

Animals↗
PubMed1991

[The morphometric characteristics of the blood microcirculatory bed of the ovary and uterine tube in rats with aseptic inflammation and after the use of a carbon-mineral sorbent].

Morphometrical investigation of the blood microcirculatory bed has been performed using the material from nonpregnant rats. Changes in volumetric density of the arterial and venous parts of the microcirculatory bed in the ovary and uterine tube after application of the spherical carbonate-mineral sorbent (SUMS-1) demonstrate a corregating effect of the sorption applied.

Animals↗
PubMed1990

[Quantitative characteristics of microcirculation bed in aseptic inflammation of the rat uterus and with the background of the use of carbon-mineral sorbents].

We studied the volume compactness of the arterial, capillary and venous parts of the microcirculation channel after 24, 48, 72 and 96 hours of the aseptic inflammation and after local application of the carbon-mineral sorbents in the rat's uterus. The local sorption decreased the reaction of the inflammation in the endo- and myometrium.

Animals↗
PubMedDate not supplied

[Morphology of vascularized tissue complexes after their transplantation on the vascular pedicle].

Light microscopy was used to study microvascular bed and tissue leukocytes in transplanted tissue complex on the vascular pedicle. The cause of the transplant edema was disturbed lymph flow manifesting in a significant dilation of lymph vessels and interstitial spaces. Restoration of the lymph flow and hemocirculation takes place by formation of new vessels registered in all the transplant tissue 2-8 months after transplantation. Late after the transplantation the tissues of the graft underwent progressive sclerotic transformation due to denervation and loss of specific functions of the transplanted tissues.

Adolescent↗
PubMedDate not supplied

[Changes in the iliac lymph node of the rat in aseptic uterine inflammation and during its correction].

In the lymphoid tissue of the iliac lymph node at an aseptic inflammation in the uterus the greatest changes have been revealed in 48 h from the moment, when the foreign body has been introduced. They are manifested at the tissue level (increasing content of macrophages, lymphoblasts, large lymphocytes, plasmoblasts, immature plasmocytes, mast cells, neutrophils), as well as at the organic level (increasing amount of secondary lymph noduli, increasing area of the paracortical zone, decreasing area of the cortical plateau, of the medullary intermediate sinus, medullary cords). Use of carbomineral sorbents ensures correction of the inflammation; this is demonstrated as reduction of reactive changes in the regional lymph node.

Animals↗