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Biomedical subjects

M S Lopez

Publications and source records attributed to M S Lopez.

4 recordsLinked to original sources
PubMed1994

Diagnostic and therapeutic potential of poly(benzyl L-glutamate).

Poly(benzyl L-glutamate) (PBLG) microcapsules, prepared by a solvent evaporation technique for intravenous injection, are evaluated for their potential use in diagnostic computed tomographic enhancement of liver images. The smaller microcapsules, < 3 microns, loaded with a radiopaque contrast material, ethyl iopanoate (IOPAE), produced prolonged opacification of the liver when delivered intravenously. In vivo tissue distribution studies of PBLG-131I-IOPAE (5 microCi/rat, iv) showed that liver had the highest uptake (percent of injected dose/g of tissue) among other organs 24 h postinjection. An in vitro estrogen receptor assay in pig uteri indicated that PBLG conjugated with estrone did not interfere with estrogen receptor affinity, suggesting the estrogen therapy potential of PBLG-estrone.

Animals↗
PubMed1984

Splint modification for flexor tendon repairs.

This report has discussed a modification of the Kleinert orthosis presently in use and has reviewed some of the physiological mechanisms accompanying tendon repair and the use of early controlled mobilization. The hand is an essential tool required for daily functioning and work, which is a key concept in occupational therapy. Early controlled mobilization has demonstrated some definite benefits with more rapid resumption of function. This resumption of function is important to therapists, patients, employers, families, and society-at-large. The preliminary results of ongoing evaluations suggest that use of the modified orthosis produces more effective results and perhaps a better quality functional level in the end.

Hand↗