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Biomedical subjects

M S Pinzur

Publications and source records attributed to M S Pinzur.

At least 55 records · Page 3Linked to original sources

Outpatient foot care: correlation to amputation level.

A retrospective analysis of Department of Veterans Affairs automated inpatient and outpatient records was performed for 3945 patients who underwent lower extremity amputation surgery due to peripheral vascular disease during fiscal year 1991. Demographic and clinical data were collected from reviewing patient database information for all Department of Veterans Affairs Hospitals nationwide. Patients were identified from the Physicians' Current Procedural Terminology codes for lower extremity amputations, and then divided into three groups (above the knee, below the knee, and foot and ankle) based on the most proximal level of amputation performed. Results indicate that increased use of designated foot care clinics was significantly associated with more distal level amputation surgery. Patients with above-the-knee amputations averaged 1.0 foot care clinic visit in the 2 years prior to amputation, whereas below-the-knee and foot and ankle amputees averaged 2.8 and 5.3 foot care clinic visits, respectively (F[df = 2,3939] = 94.20, P < .05). The same finding was noted when only users of foot care clinics were examined. Patients with a codiagnosis of diabetes were more likely to undergo distal amputation than those with other diagnoses (P < .05). The results of this study suggest the potential effectiveness of designated foot care clinics in preserving limb length in individuals with peripheral vascular disease and diabetes.

Adult↗

A treatment algorithm for neuropathic (Charcot) midfoot deformity.

Forty-nine feet in 47 patients with midfoot neuropathic foot deformity were referred for care to a comprehensive foot salvage clinic and followed for an average of 3.6 years. Twenty-three initially presented without open ulcers. Two underwent elective Syme's ankle disarticulation amputation, and the others were kept ambulatory with a combination of periods of nonweightbearing cast immobilization, accommodative extra-depth shoes with custom orthotics, and ankle-foot orthoses. Twenty-six of the feet initially presented for care with open ulcers and/or chronic osteomyelitis. Twenty-two of these patients underwent 32 surgical procedures. Sixteen underwent debridement of the infected bone and surrounding soft tissues. Excision of large, nonaccommodative boney prominence, termed exostectomy, was performed in eight. Partial excision of the deformed midfoot combined with boney stabilization and attempted arthrodesis, termed partial tarsectomy, were performed in seven. All surgical patients were managed postoperatively with long-term custom accommodative bracing. Follow-up at an average of 3.6 years revealed that all but one of the patients remained ambulatory. Six walk with accommodative shoe gear and persistent stable chronic open ulcers. None required below-knee amputation. Five amputations were performed, three at the Syme's ankle disarticulation level, one at the Chopart's hind-foot level, and one at the mid-foot level.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Transcutaneous oxygen tension in the dysvascular foot with infection.

Eight adult insulin-requiring diabetics with peripheral vascular disease were admitted with foot infection and signs of systemic sepsis. Transcutaneous oxygen tension was measured at the foot and ankle prior to surgery. None of the values were sufficient to support wound healing. Four of the patients underwent open ray resection and four open midfoot amputation. After resolution of the local infections, transcutaneous oxygen tensions were repeated. Seven of the eight patients exhibited an appreciable increase in the value following decompression of the foot infection, sufficient to support wound healing.

Adult↗

Gait analysis of dysvascular below-knee and contralateral through-knee bilateral amputees: a preliminary report.

Four elderly peripheral vascular insufficiency below-knee amputees, average age 58, underwent contralateral through-knee amputation for gangrene. All four became household ambulators with end-weight bearing designed prosthetic sockets and four-bar linkage knees. Gait analysis was performed with two AMTI (Newton, Mass) Biomechanics Force Platforms and a Watsmart Motion Monitoring System (Waterloo, Ontario). All four were observed to apparently "lock" the four-bar linkage prosthetic knee into extension during midstance and double limb support phases of gait. All subjectively felt that their through-knee limb was their more stable limb. Weight-bearing occurred during 63% of the gait cycle on the below-knee limb, 54% on the through-knee limb, and 17% in double limb support. Walking propulsion, as measured by forefoot impulse, was similar in the two limbs. The first peak of vertical force, corresponding to the elevation of the center of body weight as it passes over the weight-bearing limb, averaged 98% of body weight on the through-knee limb and only 93% on the below-knee limb. The second peak, corresponding to the kinetic energy of the falling trunk and muscle function providing linear acceleration of the center of body weight during propulsion, averaged 96% of body weight on the through-knee limb, and only 73% on the below-knee limb. Progression of the center of pressure, a qualitative measure of limb stability, was more orderly in the through-knee limbs.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Gait analysis in peripheral vascular insufficiency through-knee amputation.

Due to recent improvements in prosthetic limb componentry, through-the-knee (knee disarticulation) amputation has gained new interest for rehabilitation-minded amputation surgeons. Recent objective scientific studies from our gait analysis laboratory have described the walking characteristics of peripheral vascular insufficiency through-knee amputees, and have compared their function with similar patients amputated above (transfemoral), or below (trans-tibial), the knee joint. This paper provides a summary of that available information.

Amputation, Surgical↗

Amputations in the diabetic foot and ankle.

Scientific structured foot salvage clinics will provide surgeons with a large population of peripheral vascular insufficiency patients who may someday become candidates for salvage amputation at the foot or ankle level. This article presents the technology of functional amputation levels.

Amputation, Surgical↗

Amputation level selection in the diabetic foot.

Walking independence in the diabetic patient with gangrene or infection can be maintained with a conservative program of distal amputation. Patients are preevaluated for their rehabilitation potential. The biologic amputation level (the most distal functional amputation level with a reasonable potential to heal) is determined by a measure of vascular inflow, tissue nutrition, and immunocompetence. By combining wound-healing potential with rehabilitation potential, one can determine the amputation level that will most likely optimize function.

Amputation, Surgical↗

Functional outcome of below-knee amputation in peripheral vascular insufficiency. A multicenter review.

A retrospective functional outcome study was performed on 299 patients treated with below-knee amputations for peripheral vascular disease during a three-year period in six Veterans Administration special amputee centers. Sixty-one percent of the patients were diabetic, and 25% were previously unilateral amputees. Surgery was performed with a long posterior flap in 92.3%, sagittal flaps in 20%, and guillotine open technique in 5.7%. Wound management was accomplished with rigid plaster dressings in 75.3%, pneumatic compression dressing in 14%, and soft dressings in 10.7%. At follow-up evaluation one to two years later, 36.1% had died. Thirteen percent suffered wound complications, with 6.7% requiring revision to a more proximal amputation level. Eighty-seven percent of community ambulators maintained their ambulatory status. A comparable percentage maintained their ability to walk with a prosthesis.

Amputation, Surgical↗

Dynamic electromyography in functional surgery for upper limb spasticity.

Surgery to improve upper limb function after stroke, closed head injury, or other causes of acquired spasticity is generally accomplished by a combination of muscle transfer, lengthening, and/or release. Dynamic electromyography can be used to identify voluntary muscle action, delineate the deforming motor forces when spasticity is present, and provide guidance for surgical planning to improve prehensile hand function.

Arm↗

Transcutaneous oxygen as a predictor of wound healing in amputations of the foot and ankle.

Thirty-eight amputations of the foot and ankle were performed in patients with peripheral vascular insufficiency over a 20-month period. Amputation level selection was based on clinical examination, a minimum ankle-brachial index of 0.5 as a measure of vascular supply, serum albumin of 3.0 gm/dl as a measure of tissue nutrition, and a total lymphocyte count of 1500 as a measure of immunocompetence. Transcutaneous oxygen tension was measured at the midfoot and ankle levels prior to surgery. Thirty-two of 38 patients (84.2%) healed their amputation wounds. When the transcutaneous oxygen tension was greater than 30 mm Hg, 24 of 26 patients (92.3%) healed. When the value was below 30 mm Hg, only eight of 12 patients healed. When the propensity to support wound healing is factored out, with patients having the metabolic capacity to heal an amputation wound in the foot and ankle, it appears that transcutaneous oxygen tension is an accurate measure of vascular inflow to support amputation wound healing.

Adult↗

Energy demands for walking in dysvascular amputees as related to the level of amputation.

Cardiac function and oxygen consumption were measured in 25 patients who underwent amputation for peripheral vascular disease (PVD), and in five similarly aged control patients with PVD. Five patients at each of the midfoot, Syme's, below-, through-, and above-knee amputation levels and the five controls were measured at rest, normal walking speed, and maximum walking speed on a treadmill. At normal walking speed, all of the patients functioned at approximately 80% of their cardiac capacity. Normal walking speed and cadence decreased and oxygen consumption per meter walked increased with more proximal amputation. The ratio of cardiac function and oxygen consumption at normal walking speed as compared with at rest increased with more proximal amputation, and the capacity to increase walking speed and oxygen consumption lessened. Our results suggest that peripheral vascular insufficiency amputees function at a level approaching their maximum functional capacity. At more proximal amputation levels, the capacity to walk short or long distances is greatly impaired.

Amputation, Surgical↗

Multidisciplinary preoperative assessment and late function in dysvascular amputees.

During a three-year period, 95 adults were treated by lower-extremity amputations for peripheral vascular insufficiency. A multidisciplinary team for presurgical evaluation determined all to be potentially independent walkers with a prosthesis. Patients were graded for level of independent walking before amputation and again at a minimum two-year follow-up examination using a seven-level functional grading system. Seventy-six of 90 patients (84%) ambulated within one functional level of their preamputation status. This return to preamputation level of function was maintained whether comparing preamputation functional level or surgical amputation level. Prosthetic use increased and the use of walking aids decreased with increased functional ambulation levels, but did not correlate with surgical levels. Peripheral vascular insufficiency patients can maintain walking independence. Multidisciplinary presurgical evaluation helps selection of the amputation level and correct prosthetic limb fitting.

Adult↗

Partial calcanectomy for the treatment of large ulcerations of the heel and calcaneal osteomyelitis. An amputation of the back of the foot.

Twelve patients who had a large ulceration over the heel were managed with a partial calcanectomy, in lieu of a below-the-knee amputation, after unsuccessful non-operative treatment of the ulcer. Only patients who had an ankle-arm index (the ratio of blood pressure at the ankle to the brachial blood pressure) of more than 0.45, a transcutaneous PO2 of more than twenty-eight millimeters of mercury (3.7 kilopascals), a level of albumin of more than 3.0 grams per deciliter (thirty grams per liter), and a total lymphocyte count of more than 1500 were managed with a partial calcanectomy. The primary diagnosis was diabetes in seven patients, peripheral vascular disease in three, quadriplegia in one, and myelodysplasia in one. The duration of follow-up averaged thirty-three months and ranged from seven to sixty-four months. The wound healed after the partial calcanectomy in ten of the twelve patients. Nine of these ten patients maintained the level of mobility that they had had preoperatively. (One patient was unable to walk because he was quadriplegic before the operation). The wound did not heal in two patients, and those patients ultimately had a below-the-knee amputation and a decrease of one grade on the scale that was used to evaluate walking ability.

Adult↗

Flexor origin release and functional prehension in adult spastic hand deformity.

Eighteen adult patients with spastic hand deformities underwent release of the flexor-pronator origin and step-cut lengthening of the flexor pollicis longus to improve prehensile hand function. The goal of surgery was to provide active grasp release in order to improve hand function. Using a previously published grading scale, patients were graded before and after operation. At follow-up after an average of 35 months (range 24-64 months), all had improved by at least two functional levels.

Adolescent↗

Loading of the contralateral foot in peripheral vascular insufficiency below-knee amputees.

Seven ambulatory peripheral vascular insufficiency below-the-knee amputees underwent gait analysis to determine the local pressures on seven prominent plantar regions in their remaining limb. Patients occupied significantly less stance phase time on their remaining limbs. Peak, mean, and total pressures measured at each of the seven prominent areas was decreased as compared with laboratory age and sex matched controls. The results of this study suggest that the risk of contralateral limb amputation surgery is related to systemic peripheral vascular insufficiency or local factors, and not increased loading of the remaining contralateral "limb-at-risk."

Aged↗

Syme's two-stage amputation in insulin-requiring diabetics with gangrene of the forefoot.

Thirty-five insulin-requiring adult diabetic patients underwent 38 Syme's Two-Stage amputations for gangrene of the forefoot with nonreconstructible peripheral vascular insufficiency. All had a minimum Doppler ischemic index of 0.5, serum albumin of 3.0 gm/dl, and total lymphocyte count of 1500. Thirty-one (81.6%) eventually healed and were uneventfully fit with a prosthesis. Regional anesthesia was used in all of the patients, with 22 spinal and 16 ankle block anesthetics. Twenty-seven (71%) returned to their preamputation level of ambulatory function. Six (16%) had major, and fifteen (39%) minor complications following the first stage surgery. The results of this study support the use of the Syme's Two-Stage amputation in adult diabetic patients with gangrene of the forefoot requiring amputation.

Adult↗

Dynamic electromyography in active and limited walking below-knee amputees.

Walking electromyography was performed in 12 below-knee amputees, who were amputated for peripheral vascular insufficiency. All were at least 1 year post-surgery and had no problems with the fit of their prostheses. Seven were community walkers and five were limited household ambulators. The quadriceps and hamstring muscles exhibited electrical activity during 60% and 64.7% of the gait cycle, respectively, in the active walkers, compared with 44.6% and 53.8% in the limited walkers. Quadriceps muscle activity was initiated almost 10% earlier in the active walkers, while hamstring muscle initiation was similar in both groups. The active walkers were able to maintain quadriceps and increase hamstring muscle activity to compensate for their absent ankle motors, while the limited walkers showed decreased activity in both muscle group. The results of this preliminary study suggest that the dysvascular limited walking below-knee amputee does not use the quadriceps and hamstring muscles for propulsion during walking, and does not appear to reap the benefits of knee joint preservation.

Aged↗

Sciatic nerve block for residual limb pain following below-knee amputation.

Ten adult patients with diffuse nonphantom limb pain in the residual limb following below-knee amputation underwent from one to four sciatic nerve blocks for the treatment of that pain. Amputation had been performed for peripheral vascular insufficiency in eight patients and for problems resulting from open fractures in two. None of the patients had responded to prosthetic modification, oral medication, or transcutaneous nerve stimulation for treatment of their pain. At one-year following treatment with sciatic nerve blocks as described in this report, one patient had not responded well to treatment but six patients had a resolution of their symptoms, and three had less subjective pain adequate to resume their normal daily activities.

Adult↗