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Biomedical subjects

M S Savenkova

Publications and source records attributed to M S Savenkova.

6 recordsLinked to original sources
PubMed2004

[The role of chlamydial infection in development of acute respiratory diseases in children].

The examination of 245 children with respiratory diseases has detected chlamydia in 45 (18.4%) of them. Chlamydial species were identified and clinical symptoms of acute respiratory diseases (ARD) of chlamydial etiology are described. Five serological groups of patients depending on the presence or absence of chlamydial infection markers were recognized. Antibacterial drug treatment showed that most effective were sumamed, rulid and clindamycin. Long-term outcomes in relation to the kind of treatment are analysed.

Acute Disease↗
PubMed2001

[Causes of lethal outcomes in croup syndrome in children].

The paper reports 40 cases of lethal outcomes in children with croup syndrome treated in Morozov Children's Moscow City Hospital in 1985-1998. 92.5% of them died of severe pneumonia complications, 7.5%--of sepsis. 70% of the deceased were infants aged 0-2 years, 75% of them were boys. All the children had aggravated premorbid background. The sputum and organ tissues contained in most cases association of viruses with staphylococci and streptococci resistant to standard antibiotics (penicillin, ampicillin, cefazoline). The conclusion is made that children with croup died primarily of severe pneumonia complications in low systemic reactivity and bacterial-viral association of the agents resistant to the antibacterial therapy.

Child↗
PubMed1991

[Microrheologic properties of erythrocytes and parameters of vascular-thrombocytic hemostasis in newborns with perinatal pathology].

Hematocrit, thromboelastogram, aggregation capacity of platelets and red blood cells, the content of prostaglandin metabolites--prostacyclin 6-keto-PGF and thromboxane B (TxB) were studied in 70 newborns who had suffered perinatal hypoxia and localized pyo-inflammatory diseases that developed during the first week of life. It has been found that the pronounced disturbances of the peripheral blood circulation and frequent hemorrhagic complications in the infants with these diseases are closely connected with disorders in the aggregation capacity of red blood cells and platelet function due to the imbalance of the prostacyclin-thromboxane-generating system.

Blood Platelets↗
PubMedDate not supplied

[Microcirculatory hemostasis in children with insulin-dependent diabetes mellitus].

Study of microcirculatory hemostasis in children with insulin-dependent diabetes mellitus helped the authors to make new conclusions on metabolic changes underlying blood coagulation cellular factors, namely, the red cell and platelet levels. Fifty children aged 7 to 15, suffering from type I condition, were examined. Ten of these were examined during the compensation stage, 23 during decompensation without ketosis, and 17 with ketoacidosis. Twelve age-matched healthy children were controls. Noticeable disorders in the microcirculatory hemostasis system were revealed in diabetic children, these changes manifesting by changed functional activities of red cells and platelets. Reduced share of platelet deaggregation, increased red cell aggregation time, reduced thromboelastogram chronometric constant and reduction of its structural parameters may be considered as the early signs of these changes. The risk of microcirculatory hemostasis disturbances augments with the disease duration and progress.

Adolescent↗