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Biomedical subjects

M S Victoria

Publications and source records attributed to M S Victoria.

13 recordsLinked to original sources

Isoproterenol infusion in the management of respiratory failure in children with status asthmaticus: experience in a small community hospital and review of the literature.

Between January 1985 and December 1988, a total of 701 children were admitted to The Methodist Hospital, Brooklyn, NY for treatment of acute asthma. Eleven of these patients (age range between 8 months and 15 years) went into respiratory failure. All cases of respiratory failure were successfully treated with intravenous isoproterenol. Only one patient needed mechanical ventilation. Treatment with isoproterenol was safe and effective without any complications. We present our experience in the use of isoproterenol in treating children with respiratory failure secondary to status asthmaticus. A brief review of the literature is included.

Adolescent

Comparison between epinephrine and terbutaline injections in the acute management of asthma.

A randomized clinical trial comparing subcutaneous epinephrine and terbutaline injections was conducted in asthmatic children at The Methodist Hospital, Brooklyn, New York. Clinical evaluation using the Asthma Scoring System was done at baseline and serially, every 15 minutes, following injection of either drug. Reversal of wheezing, and changes in respiratory and heart rates were assessed using strict a priori criteria. The patients' differential response to both drugs was assessed by a crossover study when the same patients came subsequently for another episode of wheezing. Our results show terbutaline to be more efficacious at a dose comparable to epinephrine dose.

Asthma

Hydrocarbon poisoning: a review.

This article reviews the mechanisms of pulmonary injury associated with hydrocarbon poisoning. The evolution of clinical and radiographic changes is discussed, along with appropriate treatment. Preventing aspiration in the emergency department is the most effective therapy for these children in the first few hours after ingestion.

Accidents, Home

Primary drug resistance in children. Drug susceptibility of strains of Mycobacterium tuberculosis isolated from children during the years 1973 through 1977 at the Kings County Hospital Center of Brooklyn.

A continuing study of the frequency of primary drug resistance among children treated at the Kings County Hospital Center of Brooklyn during the years 1973 through 1977 showed a high incidence of primary drug resistance to isoniazid (8.8 per cent) and to streptomycin (12.3 per cent). In contrast, there were no strains resistant to cycloserine, viomycin, ethambutol, or rifampin, and only one of 57 strains (1.8 per cent) was resistant to ethionamide, and one (1.8 per cent) was resistant to para-aminosalicylic acid. Comparison with previous studies begun in 1961 showed no significant increase in resistance to isoniazid during 3 prior periods of study and no increase in resistance to streptomycin during the last 2 periods of study. It must be emphasized that these findings relate only to the children of a local community, and do not reflect the prevalence of primary drug resistance elsewhere in this country or among different age groups.

Adolescent

A two-year experience with cromolyn sodium in children with asthma.

A two-year experience with cromolyn sodium in children with asthma drawn from inner city population, is presented. Though the initial response to the drug at six weeks was excellent, the response over a two-year period was only very moderate. The possible reasons for this are discussed.

Asthma

Miliary tuberculosis in two infants after nursery exposure: epidemiologic, clinical, and laboratory findings.

Two infants born 4 days apart, and cared for in the same nursery, developed miliary tuberculosis at 2.5 and 5.5 months of age, respectively. A search for a source case among household contacts failed to reveal anyone with active tuberculosis. An epidemiologic study of nursery personnel revealed a nurse's aide with cavitary tuberculosis. Examination of 1,647 infants (98.9 per cent of all infants cared for in the nursery during the 10.5-month period preceding the discovery of the source case) failed to reveal any other infected children. Recommendations are made for tuberculosis control programs among nursery personnel that should be carefully and persistently followed.

Adult