POLYLYSINE-SPECIFIC ANTIBODIES AND THEIR REACTION WITH OLIGOLYSINES.
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Biomedical subjects
Publications and source records attributed to M SELA.
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A multichain copolypeptide, p(Tyr,Glu)-pAla--pLys, induced in guinea pigs a prolonged state of delayed hypersensitivity not associated with detectable circulating antibodies. Cross reactions of the delayed type were observed with chemically related polypeptides.
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The injection of two synthetic polypeptide antigens into adult rabbits treated with 6-mercaptopurine, or into newborn rabbits, resulted in immunological "unresponsiveness" to subsequent immunizations with these antigens. The "tolerant" animals were shown to be reactive toward the non-related antigen ovalbumin.