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Biomedical subjects

M Saba

Publications and source records attributed to M Saba.

21 records · Page 2Linked to original sources

Spinal cord compression in neuroblastoma.

Twelve of 80 patients suffering from neuroblastoma who were treated during a 21-year period had intraspinal involvement. Mediastinal tumors have a greater tendency to extend to the spinal canal; however, distant spread of the tumor is rare in patients presenting with intraspinal extension. Patients with intraspinal extension also survive longer than those without. Other factors affecting survival are age, stage of disease, duration of neurological symptoms, degree of histologic differentiation, and mode of therapy. In the absence of osseous metastasis, total excision of the primary lesion and its intraspinal components is usually followed by a favorable outcome; residual neurological deficits among survivors, however, are relatively common.

Child↗

Arginine deficiency-induced hyperammonemia in a home total parenteral nutrition-dependent patient: a case report.

BACKGROUND: Patients with short bowel syndrome and renal dysfunction with TPN dependence are at high risk for developing hyperammonemia if the TPN does not contain sufficient quantities of arginine. Providing proper nutrition support is essential in the management of these patients. METHODS: We report on a patient with short bowel syndrome, TPN dependence, and normal renal function who developed hyperammonemic encephalopathy due to inadvertent lack of arginine in his TPN. RESULTS: The patient was successfully treated with hemodialysis and an IV arginine infusion to resolve the hyperammonemia. His home TPN was also adjusted such that arginine was added to his subsequent solutions. CONCLUSIONS: Our patient underscores the importance of adequate and sustained arginine supplementation to avoid hyperammonemia in TPN dependent patients with short bowel syndrome.

Adult↗

Examination of the damping behavior of IMZ implants.

The damping behavior of 392 IMZ implants with a diameter of 4 mm was examined by performing Periotest measurements during regular implant follow-up. The results were correlated with radiographically assessed peri-implant bone reduction. To guarantee statistical independence, only one randomly chosen implant per patient was considered in the examination. In 167 implants, the difference between the mean mandibular and maxillary Periotest values proved to be statistically significant. Age, sex, and radiographic length of the endosseous part of the abutment had no influence on the Periotest values. Assessment of the Periotest values can thus be considered an additional parameter for objective determination of IMZ implant success. However, exclusive use of the Periotest method without additional radiographic examinations does not seem to be justified.

Adult↗