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M Sabrià-Leal

Publications and source records attributed to M Sabrià-Leal.

8 recordsLinked to original sources
PubMed1998

Comparative study of the clinical presentation of Legionella pneumonia and other community-acquired pneumonias.

The aim of this study was to compare the clinical, biological, and radiologic features of presentation in the emergency ward of community-acquired pneumonia (CAP) by Legionella pneumophila (LP) and other community-acquired bacterial pneumonias to help in early diagnosis of CAP by LP. Three hundred ninety-two patients with CAP were studied prospectively in the emergency department of a 600-bed university hospital. Univariate and multivariate analyses were performed to compare epidemiologic and demographic data and clinical, analytical, and radiologic features of presentation in 48 patients with CAP by LP and 125 patients with CAP by other bacterial etiology (68 by Streptococcus pneumoniae, 41 by Chlamydia pneumoniae, 5 by Mycoplasma pneumoniae, 4 by Coxiella burnetii, 3 by Pseudomonas aeruginosa, 2 by Haemophilus influenzae, and 2 by Nocardia species. Univariate analysis showed that CAP by LP was more frequent in middle-aged, male healthy (but alcohol drinking) patients than CAP by other etiology. Moreover, the lack of response to previous beta-lactamic drugs, headache, diarrhea, severe hyponatremia, and elevation in serum creatine kinase (CK) levels on presentation were more frequent in CAP by LP, while cough, expectoration, and thoracic pain were more frequent in CAP by other bacterial etiology. However, multivariate analysis only confirmed these differences with respect to lack of underlying disease, diarrhea, and elevation in the CK level. We conclude that detailed analysis of features of presentation of CAP allows suspicion of Legionnaire's disease in the emergency department. The initiation of antibiotic treatment, including a macrolide, and the performance of rapid diagnostic techniques are mandatory in these cases.

Adult↗
PubMed1991

[Bacteremia from Campylobacter fetus. Increasing interest and incidence].

Three bacteremias of Campylobacter fetus were described. One was a male patient and two were females. Underlying illnesses were present in all of them (Hodgkin disease, AIDS and hepatic cirrhosis respectively). They were all admitted because of fever and no other symptoms of infectious focus were present. Physical findings were not relevant. The blood cultures became positive in days 6, 7 and 9 respectively. Antibiotic treatments were not standardised, so no conclusions can be drawn. The evolution was correct except for the patient infected by the human immunodeficiency virus who carried out a recurrent course. The authors comment on the increasing interest of this pathogen causing extraintestinal infection.

Aged↗
PubMed1989

[A prospective study of 57 cases of Mediterranean boutonneuse fever].

Mediterranean boutonneuse fever (MBF) is an uncommon acute infective disease characterized by the development of an inoculation lesion followed by fever and maculo-papular erythematous rash. In the present study we have evaluated the epidemiological, clinical and laboratory abnormalities of 57 cases of MBF diagnosed in our Hospital during a 2-year period. Although incidence does not appear to increase, our series shows that MBF is a common disease in our area. On the whole, MBF is a benign condition; however, torpid forms are increasingly reported. Therefore, a rational therapeutic approach questioning the validity of single therapeutic doses is required, particularly for adults.

Adolescent↗
PubMed1988

Functioning metastases of a nonfunctioning paraganglioma.

A case of nonfunctioning paraganglioma, initially qualified as benign, is described. Two years following extirpation, functioning bone and lung metastases were manifested by hypertensive crises and increased levels of vanilmandelic acid and catecholamines in urine. The criteria for benign and malignant paragangliomas are discussed with regard to functional transformation of the tumor described in this case. It is concluded that the phenotypic heterogeneity of the primary tumor cells could explain the difference in biological behavior of the primary tumor and its metastases.

Adult↗