DHEA, a selective glucocorticoid receptor antagonist: its role in immune system regulation and metabolism.
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Biomedical subjects
Publications and source records attributed to M Saccò.
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The authors refer about a case of mucocele contained in a strangled properitoneal inguinal hernia and they discuss its pathogenesis.
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On the basis of their own experience, totaling 540 examinations, the authors explain the advantages offered by the medium-length (100 cm) optical fibroscope in the diagnosis of colonic diseases. They claim that the instrument under discussion is the most complete, being at once sturdy and easy to use and affording, despite its limite length, exploration of the ascending colon in 53.3% of the cases--a procedure for which the indications are on the other hand fairly limited.
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In a group of 129 female patients with nodular goiter, Graves' disease and primary hypothyroidism, the PRL and TSH secretions were studied in parallel. Concurrent changes in the two hormones were evident only in conditions of marked hyper- or hypothyroidism. In the patients with non-toxic nodular (single or multiple) goiter the TSH showed low or normal values, while the PRL appeared normal or elevated. From these results two important conclusions can be drawn: 1. the T3 and T4 levels interact with PRL secretion concomitantly with TSH only when they undergo a huge deviation from the normal range; 2. the goitrogenic action of PRL that has been reported in experimental animals cannot be excluded in man.
INTRODUCTION: The interest in clinical investigations in health-related quality of life (HRQoL) of aging men has increased over recent years, particularly in the context of partial androgen deficiency. The aim of this paper is to inform the scientific community about a harmonized Italian Aging Males' Symptoms (AMS) scale. METHODS: There were two slightly different Italian AMS scales, which both underwent an up-to-date linguistic & cultural translation process, i.e., were both valid to be applied in clinical research. However, there are potential long-term problems associated with having two Italian language versions of the scale in the same country. Therefore, an ad hoc committee of key persons related to both versions met with the scale's developer, to create a harmonized single Italian AMS. RESULTS: The harmonization meeting came up with a consensus item-by-item and the new Italian reference scale was agreed upon. It was decided that this scale should be published to avoid any confusion among future users. CONCLUSION: The Italian AMS scale published in this paper should be used for future clinical and other research.
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