[Early testicular neoplasms in children: embryonal carcinoma].
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Biomedical subjects
Publications and source records attributed to M Salas Martínez.
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Fatal cases of toxoplasmosis seen at the Hospital Infantil de México between 1943 and 1973, together with postmortem studies are reviewed. There were five postmortem studies where it was possible to identify toxoplasma in histologic lesions. Clinical manifestations were grouped in pictures; thus, the infectious picture, the intracranial hypertensive, the neurological and the meningeal pictures were made up. In all five cases of this small group, toxoplasma was identified within and without parasitized cells and was found specially abundant in the central nervous system. Considering the early initiation of neurological manifestations and the intensity of encephalic lesions, it may be assumed that all five cases of prenatal toxoplasmosis. The reason why an infection so usually light in the mother is able to cause a disease so severe in the fetus seems to have an explanation on the fact that toxoplasma increases in virulence when reaching the product as second-step infection. In all five cases, the intensity of the lesions agrees with the severeness of the clinical picture and with the early manifestations following birth. The parasite was identified in the brain in all cases and in some of them, in the liver and lungs.
From a series of 4,147 postmortem studies, there were 2,280 cases of infectious processes as responsibility of death out of which, 647 corresponded to the digestive tract. Within the group of digestive tract infections, 283 were of bacterial nature and within this last group, there were 43 cases of shigellosis. Included in the fatal cases of shigellosis is the description of their description by ages and sexes; the types of enteropathogenic germs identified in the course of disease and at postmortem studies are mentioned and special reference is made to the type and localization of lesions within the digestive tract. Also, the type and localization of extraintestinal lesions, directly or indirectly related with shigellosis are described. Pathological processes considered as immediate cause of death are pointed out and from the group is extraintestinal infections, the germ identified in each as responsible of death is mentioned. Finally, a brief outline is made of the clinicopathological correlation.
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In order to determine the proportion of congenital neoplasias, a study of 1 076 malignant neoplasias was carried out at the Pathology Department of the Hospital Infantil de Mexico. As unquestionably congenital malignant neoplasias were considered those detected since birth and as possibly congenital, those identified during the first year of life of the patient. As a whole, in this series of neoplasias, approximately one case was found of the sum of the congenital group and the possibly congenital, to 4.5 of the total series. However the proportion of the group of congenital malignant neoplasias and that of possibly congenital varied for each type of neoplasias in particular. Excluding malignant neoplasias of hematopoietic tissues, retinoblastoma, nephroblastoma and neuroblastoma were the malignant neoplasias most frequently found.