M Salvadores | PubMed Health

PubMed1987

[Transurethral resection using glycine irrigation].

An accident is described which occurred during a transurethral resection of a prostatic adenoma using a 1.5% glycine solution in a 68 yr old patient. The surgery was performed under spinal anaesthesia with bupivacaine. After 14 l of irrigation fluid had been used, visual disturbances, bilateral mydriasis and drowsiness appeared, with no haemodynamic disturbances. Three hours after the end of surgery, there appeared convulsions, with the blood sodium level at 118 mmol X l-1. Symptomatic treatment resolved the problem, and the clinical examination was normal 12 h after surgery. The role of hyponatraemia in the clinical state is discussed. The usefulness of regional anaesthesia in the early detection of this type of accident is recalled.

Aged↗

PubMedDate not supplied

[Comparison of thiopental and propofol in short-duration anesthesia].

Forty healthy females, 18 to 65 years, undergoing diagnostic or therapeutic uterine curettage were studied with the purpose of comparing anesthetic characteristics of thiopental and propofol as induction agents. They were randomly allocated in two groups: A propofol induction group (2.5 mg/kg), and a thiopental induction group (4-5 mg/kg). Fentanyl (2 micrograms/kg), was administered 2 minutes before anaesthesia, and N2O/O2 (66%/33%) by mask was maintained during surgery. Changes in systolic and diastolic BP were not significantly different in two groups. The HR decreased more significantly in the propofol group (20% vs 10%; p less than 0.005). Apnea was significantly greater in the propofol group, in term of incidence (50% vs 15%; p = 0.025), and duration (92 seg vs 17 seg; p = 0.20). The lapses of time to opening the eyes and response to a command were not significantly different, but the time to be able to seat was significantly lower in the propofol group (12 min vs 21 min; p = 0.0003). Anaesthesia was clinically satisfactory for most patients in both treatment groups.

Adolescent↗