[Tropical actinic lichen or disseminated discoid lupus erythematosus in a child].
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Biomedical subjects
Publications and source records attributed to M Samsoen.
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322 new cases of leprosy in France are registered by a postal survey among 11 towns, from 1970 to 1978. 217 are detected in Paris, 105 in other parts of France. 137 are foreigners, 104 come from overseas French territories, 45 are reapatriated French nationals. 39.7% are lepromatous, 43.6% tuberculoid, 13.9% indeterminate. 35 cases are followed out of which 16 cases in Alsace were discovered in Strasbourg.
A comparative study of the results of skin tests and tests in vitro (lymphocyte transformation L.T. and R.A.S.T. for specific IgE) in 21 patients allergic to penicillin or penicillin-derivates revealed that tests in vivo are more sensitive and reliable than L.T. and R.A.S.T. This discordance needs future research for more valuable tests in vitro, such as specific histamine-release by leucocytes or determination of IgG4 reagins by R.A.S.T. procedure. A method of diagnosis of betalactamin hypersensitivity by skin tests, including penicilloylpolylysine, benzyl-penicillin, ampicillin and cephalosporin, is suggested; this method was experienced in 21 patients and 23 control subjects and proved to be safe and reproducible.
3 induced eczemas during systemic drug administration are reported: 2 were caused by methyldopa, 1 by clofibrate. The relationship is established either by patch-tests or by administration of the drug.