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Biomedical subjects

M Santori

Publications and source records attributed to M Santori.

At least 19 recordsLinked to original sources
PubMed1986

[Level of protection against tetanus in an outpatient population].

Protection levels against tetanus toxin were estimated in 332 patients, at our Laboratory, by means of the passive haemagglutination with turkey erythrocyte test. The testing showed that the protection level decreases with age, it is higher among males in those over 30 yrs; roughly 10% of those who were not vaccinated were protected. Furthermore, it has been demonstrated that in some cases the protection level remains high even after a long period of time since the last vaccination, whereas a certain percentage of the recently vaccinated patients is not protected; consequently the effectiveness of the vaccination must be checked by measuring the antibody titers.

Adult↗
PubMed1982

Coagulation and platelet activation after retinal vein occlusions.

The role played by coagulation and platelet activation in the pathogenesis of retinal vein occlusions (RVO) has been evaluated by measuring beta-thromboglobulin (B-TG), circulating platelet aggregates (CPA), thromboxane B2 (TxB2) and fibrinopeptide A (FPA) in 25 patients less than 40 years old, investigated after the acute phase of RVO. FPA nd B-TG were significantly higher than in healthy subjects; CPA and TxB2 were not different. These abnormalities, found in patients free from apparent generalized vascular disease, suggest that a thrombophilic state characterized by coagulation and platelet activation is present in a high proportion of young patients with RVO.

Adolescent↗
PubMed1981

[Retinal vascular changes and haemostatic function in young patients (author's transl)].

Haemostatic function was studied in 40 patients between one and 12 months from the occurrence of retinal vein occlusion (RVO); 25 patients aged 40 years, or less and 15 were more than 45 years old. The following tests were performed : plasma beta-thromboglobuline (beta-TG) fibrinopeptide A (FpA), PTT, spontaneous in vitro platelet aggregation (SpA), circulating platelet aggregates (CPA), platelet retention (PR) to glass beads, serum thromboxane B2 (TxB2). In the group of older patients, there was a significant increase of beta-TG, FpA, PR, SPA, TxB2, and a reduction in the PTT. CPA was not significantly changed. In the group of younger patients (less than 40 yrs) only FpA and beta TG levels showed significant differences from the control group of age-matched healthy subjects. These findings suggest that the alterations present in older patients are likely to be secondary to generalized vascular damage, whereas a state of activation of the coagulation system appears to be present in younger patients with RVO.

Adult↗