[Cholesterol, inborn errors of lipid metabolism and ischemic heart disease in the light of epidemiological studies].
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Biomedical subjects
Publications and source records attributed to M Santrůcek.
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A survey concerning 15 years' experiences with the screening of the ischaemic heart disease and the arterial hypertension in selected male age groups in Prague is given. Here the authors entered an international study, in which the possibilities of the primary prevention of the ischaemic heart disease and its complications were investigated by means of clofibrate. As a preliminary result a reduction of serum cholesterol, which was increased over 279 mg/100 ml, by 13% and in values between 279 and 260 mg/100 ml by 8.8% could be established. With the help of screenings not only the incidence and the prevalence of the examined disease in the population, respectively, were established, but at the same time factors of risk were found, the elimination of which may shift the beginning of the disease or fully prevent its development.
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