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Biomedical subjects

M Satapathy

Publications and source records attributed to M Satapathy.

11 recordsLinked to original sources
PubMed1991

Haptoglobin phenotypes in diabetes mellitus and diabetic retinopathy.

An analysis of haptoglobin (HP) phenotypes in 81 cases of diabetes mellitus (DM) without retinopathy and 122 cases with diabetic retinopathy (DR) were studied in relation to 180 normal and healthy controls matched for age and sex. A significant decrease in HP 2-1 frequency was found, suggesting protection for heterozygotes in both DM and DR (with a relative risk of about 0.31). As an acute-phase reactant HP may be functionally involved in the etiology of DM and DR, which are associated with immunologic and inflammatory processes, respectively. No significant differences were found with respect to sex, age at onset, duration of DR, types of DM and DR, and family history.

Alleles↗
PubMed1990

Iron in sickle cell disease.

Iron deficiency anaemia was detected in 23% of cases with homozygous sickle cell disease. The aetiology of iron deficiency was similar to the other population in the community. High serum ferritin level was detected in 15.4% of the cases and was well correlated to the number of transfusions. Tissue haemosiderosis was not detected in any case. Patients with heterozygous sickle cell had either normal or low serum ferritin levels.

Adolescent↗
PubMed1981

Copper metabolism in retinitis pigmentosa patients.

Serum copper, ceruloplasmin, and urinary copper were estimated in 13 normal subjects and 24 patients with primary retinitis pigmentosa. The serum copper levels in patients appeared to be higher and ceruloplasmin levels lower than in the normal subjects. The patients seem to fall into 2 categories with regard to urinary copper. About a third of them excreted 2-4 times more copper in the urine, while in the others the excretion is comparable to normal subjects. It appears possible that there exists in India a genetic isolate of retinitis pigmentosa with altered copper metabolism. The distribution of these patients may be different between the northern and southern parts of the country.

Adolescent↗
PubMed1980

Dermal ridge configurations in retinal detachment.

An analysis of dermal ridge configuration in 95 retinal detachment patients showed characteristic association with different aetiological bases of the condition like myopia, aphakia, vitreous degeneration and idiopathic factors. The study revealed a significantly high frequency of whorls on fingers and low mean interdigital ridge counts in the patients as compared to controls. Aphakic detachments showed maximum and vitreous degeneration detachments minimum variation from controls for all characters except the main line terminations. Of all the parameters studied, main line terminations contributed maximum for the variation between the detachment types. The results are discussed in light of the contribution of dermatoglyphic characters to the aetiology of retinal detachment.

Adult↗