Influence of certain drugs on the permeability of sulphadiazine across the blood brain barrier.
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Biomedical subjects
Publications and source records attributed to M Sayeed.
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Sixty two adults, including forty one males (16-36 yrs.) and twenty one females (16-25 yrs.), were studied by closed circuit method as regards their B.M.R. Males showed a greater lowering of metabolism than the females when compared to MF and AD standards. The females actually showed a higher B.M.R. than the RR standards. Both the sexes had a higher basal metabolism than the value reported from other parts of the country. The difference, however, was significant only in the case of females. Winter metabolism was not sigificantly higher than the summer value in either sex, though females showed some what greater variation.
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Serum sialic acid estimation was done in 97 pregnant and 61 non-pregnant healthy women. A progressive rise in the level was observed as the pregnancy advanced. The rise was higher in subjects above 30 years of age. Non-pregnant women weighing more than 50 kg a significantly higher serum sialic acid level, but the contrast was reversed during pregnancy and puerperium.