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M Schüllerová

Publications and source records attributed to M Schüllerová.

At least 19 recordsLinked to original sources
PubMed1990

[Vascular pathology in the extracranial segment of the carotid arteries in patients with various stages of vascular hypertension].

The aim of the work was to assess the frequency, localization and degree of pathological changes in the extracranial segment of carotid arteries in patients in different stages of hypertension by using ultrasonic diagnosis. The authors examined 115 hypertonic patients stage I and II and 95 hypertonic patients stage III according to the WHO classification. They compared the results with a group of 20 subjects, healthy from the clinical and biochemical aspect. The examinations were made by means of an Exhoflow II apparatus of Diagnostic Electronic Corporation, using the method described by Traubner (16). The findings in the control group were normal. In the hypertonic patients stage I and II in 15 (13%) mild, haemodynamically insignificant changes were recorded. In the hypertonics stage III 31 (32.6%) had a pathological finding, incl. 16 patients (16.8%) who had severe stenotic changes, serious from the haemodynamic aspect.

Blood Flow Velocity↗
PubMed1976

Effect of autonomic blockers on the heart rate of intact rats and animals with artificial hyperthyroidism.

The effect of various autonomic blockers on the heart rate (from the ECG recording) of intact rats and of animals with experimental hyperthyroidism induced by the administration of dried thyroid was studied. In intact rats, the heart rate fell significantly (by 22%) during the first week after the peroral administration of propranolol (0.05% in food), but trimepranol (0.02%), reserpine (0.001%) and guanethidine (0.1%) had no effect (in a suplementary experment, a small, but statistically significant decrease was also found after trimepranol). In experimental hyperthyroidism, using the same blocker doses, the heart rate fell significantly after propranolol (by 23%), trimepranol (22%), reserpine (16%) and, in a preliminary experiment, guanethidine (19%). On injecting 0.05 mg propranolol intravenously, the maximum drop in the heart rate in intact rats was 22%, while in hyperthyroidism it was hardly more than half this value (at all the intervals from 2 to 30 minutes the decrease was statistically significant). Practolol, in a dose of 0.3 mg i.v., was less effective -- in intact rats the heart rate fell by not more than 12% (at all the intervals from 2 to 30 minutes the decrease was significant), but in hyperthyroidism the drop was slower and statistically non-significant. The results do not furnish an unequivocal answer to the question of the role of adrenergic regulation of the heart rate under physiological conditions and in experimental hyperthyroidism in rats.

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