Biomedical subjects

M Seabright

Publications and source records attributed to M Seabright.

28 records · Page 2Linked to original sources

PubMed1975

Variation in trypsin banding at different stages of contraction in human chromosomes and the definition, by measurement, of the "average" karyotype.

Ideograms of chromosomes obtained by the trypsin/Leishman method are presented in which the size and position of the bands of chromosomes at different stages of contraction have been defined by measurement. A hypothesis is suggested which could explain the changes observed in the banding pattern between stages of condensation.

Chromosomes↗

PubMed1975

The differential distribution of X-ray induced chromosome lesions in trypsin-banded preparations from human subjects.

The distribution of X-ray induced aberrations between trypsin-banded regions within human chromosomes has been studied in over a thousand cells from normal and abnormal individuals. An analysis of this data has been performed for each type of aberration separately, taking into account the relative amount of material at risk in reach region. A number of significant deviations from expectation were detected but many of these could be explained in terms of the failure of detection of some aberrations.

Chromosome Aberrations↗

PubMed1975