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Biomedical subjects

M Seligman

Publications and source records attributed to M Seligman.

24 records · Page 2Linked to original sources
PubMed1966

Properties of bursicon: an insect protein hormone that controls cuticular tanning.

On gel filtration the retention volume of bursicon indicates a molecular weight of about 40,000. On disc electrophoresis bursicon migrates toward the anode and appears at an R(F) (relative to the marker dye) of 0.3 to 0.4. The properties of fractions with bursicon activity in blood, brain, and ganglion of a fly (Sarcophaga bullata), and in blood, ganglion, and corpora cardiaca of a roach (Periplaneta americana) are similar, but not identical. Bursicon in the blood is more heat labile, and the activity in brain and corpora cardiaca shows two peaks in electrophoresis, instead of one as in the other fractions.

Animals↗
PubMedDate not supplied

An enhanced positive reinforcement model for the severely impaired cocaine abuser.

This article describes a cognitive-behavioral treatment approach that has been extensively modified to work with inner-city methadone-maintained cocaine users. Modifications were deemed essential to address the problems of engagement and retention in treatment that are typically encountered with this population. While this approach relies on such basic tenets of treatment as relapse prevention, cognitive restructuring, and psychoeducation, an understanding of the particular psychological vulnerabilities of this population has been incorporated into the model. The modified approach utilizes positive reinforcement extensively. This includes use of concrete reinforcers to facilitate initial engagement, and use of interpersonal reinforcers (therapist positive regard, attention, and respect) to increase program retention and sustain posttreatment change. Preliminary results indicate that 63% of patients can complete this intensive 6-month program, with considerable reductions in cocaine use and significant change in drug injection behavior.

Adult↗