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Biomedical subjects

M Seveso

Publications and source records attributed to M Seveso.

At least 37 records · Page 2Linked to original sources
PubMed1992

[Use of ultrasound-guided percutaneous nephrostomy before and after ESWL: 4 years of experience].

We evaluated the usefulness of percutaneous nephrostomy in 1700 patients treated for reno-ureteral stones by extracorporeal shock wave lithotripsy (SWL). Out of this group 81 patients (5.8%) underwent echo-guided percutaneous nephrostomy (EPCN): the procedure has been performed in local anesthesia in 38% of the cases (31 pts) before SWL and in 62% (50 pts) after. The majority of EPCN were carried out for the presence of acute or chronic ureteral obstruction with echographic evaluable dilation of pyelocaliceal system when retrograde ureteral manipulations failed or were considered unsuitable. EPCN before SWL was performed because of ureteral stone and uncomplicated pyelocalyceal dilation (19 pts); ureteral stone, pyelocaliceal dilation and fever > 38 degrees C (3 pts); ureteral stone, pyelocalyceal dilation and functional IVP exclusion (5 pts); pyelic stone in solitary kidney (1 pts); ureteral stones in pregnancy (2 pts). EPCN after SWL was performed because of uncomplicated, persistent pile-up (31 pts); ureteral pile-up complicated by fever and colics (9 pts); ureteral obstructing fragments (2 pts); double J obstruction by stone dust (3 pts); persistent ureteral pile-up around double J (3 pts); anuria in solitary kidney (1 pt). Out of the patients who underwent EPCN before SWL 13% were stone free and without drainage at discharge, 77% had passable stone fragments at discharge and drainage has been taken out at 15-30 days check up, 10% had unbroken stone and underwent with drainage to ureterolithotripsy.(ABSTRACT TRUNCATED AT 250 WORDS)

Humans↗
PubMed1992

[Comparative study of the effects of famotidine and omeprazole in the prevention of the aspiration of gastric contents syndrome in elective surgery].

This study compares the efficacy of omeprazole and famotidine in reducing gastric volume and activity. Sixty patients scheduled to undergo elective orthopaedic surgery were randomly allocated to receive famotidine 40 mg or omeprazole 40 mg at 22 hours, the night before surgery, or omeprazole at 22 hours the night before and 20 mg at 6 hours on the morning of surgery, 20 patients served as control and received no drugs. Intragastric volume and pH were measured immediately after induction anaesthesia and after surgery. Either drug reduces gastric volume. Famotidine reduces at maximum volume. Omeprazole reduces at maximum pH. Omeprazole 40 mg in some cases doesn't sufficiently reduced pH, because the interval from drug administration to induction of anaesthesia is too long. The comparably high volume of gastric content after omeprazole in single or double dose doesn't represent a risk.

Famotidine↗
PubMed1990

[Tranylcypromine and general anesthesia. Description of a clinical case].

The Authors report a collapsial reaction during general anaesthesia for total hip replacement in a patient treated with tranylcipromine, an inhibitor of MAO, as antidepressant agent. She had discontinued drug intake eight days before. Nevertheless a serious collapsial reaction appeared in association with general anaesthesia. It would be suitable, in their opinion, to stop antidepressant therapy with tranylcipromine at least three weeks (like with other IMAO) before general anaesthesia.

Aged↗
PubMed1986

Prediction of the progression of renal failure in adult and in pediatric patients with malignant focal glomerulosclerosis.

A retrospective analysis of the progression of renal failure was performed in 6 children and 5 adults with idiopathic nephrotic syndrome unresponsive to steroids and immunosuppressants and with histological findings of focal glomerulosclerosis. We analyzed the linear regression of Ccr and of their logarithmic transformation vs time (months) starting from the time when the first abnormal value was observed (t = 0). The regression analysis was performed at three different times, when Ccr was: 30-20, 20-25 and 10-15 ml/min/1.73 sqm. Extrapolation of each of these lines on the x axis predicted when renal function would be zero. The difference in months, between the predicted and actual time of starting dialysis was prediction error. "r" values were always elevated and statistically significant for both linear and logarithmic regression; there was a large intersubject variability in the rate of loss of renal function but the mean prediction error at various levels of Ccr was within limits clinically acceptable. Moreover its magnitude did not significantly decrease by prolonging the time of observation. This indicates that in this disease the decay of Ccr enters a track which proceeds linearly or logarithmically after the onset of renal failure and no major deviation from the predicted line is to be expected. The good predictability in our study may be attributed to the fact that our patients were homogeneous for a number of factors which may be relevant to progression of the disease. It confirms the view supported by Gretz et al. [1983] that there is a need for stratification of patients in large cohort studies on the predictability of loss of renal function.

Adolescent↗
PubMed1985

Influence of technical factors and different immunosuppressive regimens on kidney graft survival. Retrospective analysis on 300 kidney transplants.

300 patients underwent kidney transplantation. Uretero-neocystostomy was performed by means of the Politano-Leadbetter technique in the first 185 patients and direct ureterovesical anastomosis in the other 115 patients. Immunosuppression included conventional therapy (steroids, antilymphocyte globulins, azathioprine) and the association cyclosporine A and steroids. Retrospective analysis on these 300 patients indicates that the improved 1 year graft survival rate (85% vs 64%) we observed in the latest years has depended to the same extent, on improved surgical technique and on advent of cyclosporine A in our therapeutic protocols. Cyclosporine A at low starting doses immediately adjusted on whole blood trough levels (200-400 ng/ml) proved to be superior to other therapeutic schedules reported in this study (1-year graft survival rate: 94% vs 84%-73%). Direct ureterovesical anastomosis was characterized by a net reduction of urologic complications (2.5% vs 9.7%).

Antilymphocyte Serum↗
PubMed1981

[Clinical and statistical observations on closed chest injuries].

The importance of AR for a prompt and upkeep therapy is underlined by the Authors on the base of a statistical and clinical study about 67 cases of thoracic trauma treated from January 1975 to November 1979. The different alteration of the chest wall and surrounding structures are taken into consideration. The possible association of thoracic trauma with head trauma, severe shock and bony traumatism are also considered from a statistical and from a clinical point of view. The various therapeutic measures in case of thoracic trauma are also mentioned.

Anesthesia↗