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Biomedical subjects

M Sh Promyslov

Publications and source records attributed to M Sh Promyslov.

At least 19 recordsLinked to original sources

[Cyclic nucleotides of human and animal glial tumors].

Studies on the level of cyclic nucleotides (cAMP and cGMP) in human and animal glial tumours showed that the content of both nucleotides, especially that of cAMP, decreases in all the tumours. The cAMP/cGMP ratio also drops down. Concurrently it appears to be the most consistent parameter of nucleotide metabolism both in brain tissue and in human or animal glial tumours. The growing tumour affects cAMP and cGMP metabolism not only in the involved but also in the other hemisphere. No principal differences between human and animal tumours have been revealed in the content of cyclic nucleotides and its variation in tumour tissue.

Animals↗

[Homocarnosine metabolism in brain tissue].

In glial tumors of human brain the content of homocarnosine has been found to be lower than in brain tissue. In experimental animals cranial injury induces an increase of homocarnosine in brain tissue. Stimulation of the nervous system of traumatized animals by phenamin brings the metabolism of homocarnosine back to normal. The results of these studies make us suppose that homocarnosine is a substance involved in brain activity.

Amphetamine↗

[The influence of rabies immunization of gamma-aminobutyric acid metabolism in the brains of animals].

Subcutaneous injection to albino rats (100-120 g) of lived fixed rabies virus was accompanied by a brief marked decrease in the content of gamma-aminobutryic acid in the animals' brain. There was also an increase in the activity of gamma-aminobutyric acid alpha-ketoglutaric acid transaminase in the brain tissue of animals vaccinated with live fixed rabies virus.

4-Aminobutyrate Transaminase↗