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Biomedical subjects

M Shibu

Publications and source records attributed to M Shibu.

14 recordsLinked to original sources
PubMed2000

Squamous cell carcinoma arising in transplanted skin.

Squamous cell carcinoma arising in a skin graft is rare. Previous reports concern the use of skin in heterotopic locations namely the vagina and oral cavity. We report a case of squamous cell carcinoma, which arose in a skin graft used for resurfacing a scalp defect. The defect followed the excision of a basal cell carcinoma 11 years previously. The excision was incomplete and radiotherapy had been given. The possible pathological mechanisms for the development of a squamous cell carcinoma in transplanted skin are discussed.

Aged↗
PubMed1994

A splint for correction of congenital ear deformities.

Fourteen non-hypoplastic congenitally deformed ears were treated with a simple splint with satisfactory results in all but one. These deformities can be treated non-surgically in the early neonatal period, effectively, without anaesthetic, and with minimal cost. We confirm other reports that better results are obtained and a shorter duration of splintage is needed if treatment is started early in the neonatal period. Our neonatal paediatric colleagues and midwives should be encouraged to manage these deformities in this way, and the need for surgical correction may be largely avoided in the future.

Age Factors↗
PubMed1993

Capsular tissues of the proximal interphalangeal joint: normal composition and effects of Dupuytren's disease and rheumatoid arthritis.

Three fibrocartilages associated with the proximal interphalangeal joint are described--at the attachment of the central slip to bone, within the slip where it passes over the joint, and the volar plate. Material was obtained at surgery following trauma, Dupuytren's disease and rheumatoid arthritis. The fibrocartilages were structurally distinct and immunolabelled differently with monoclonal antibodies to extracellular matrix components. All fibrocartilages from normal and Dupuytren's fingers contained chondroitin and keratan sulphate. Type II collagen was present in all attachment zones, although there was little in rheumatoid fingers. It was also present in the dorsal hood of some normal fingers, but not in pathological specimens or the volar plate. The results show that the fibrocartilages are dynamic tissues whose composition varies according to function and use, and changes in disease.

Adult↗