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M Shiojima

Publications and source records attributed to M Shiojima.

15 recordsLinked to original sources
PubMed1997

High-level plasmid-mediated gentamicin resistance and pheromone response of plasmids present in clinical isolates of Enterococcus faecalis.

Eleven pheromone-responding plasmids encoding erythromycin or gentamicin resistance were isolated from multiresistant clinical Enterococcus faecalis isolates. The plasmids were classified into six types with respect to their pheromone responses. The three erythromycin resistance plasmids responded to different pheromones. Of the eight gentamicin resistance plasmids, four plasmids responded to same pheromone. Southern hybridization studies showed that the genes involved in regulation of the pheromone response were conserved in the drug resistance plasmids.

Anti-Bacterial Agents↗
PubMed1993

Layer thickness in panoramic radiography as defined by different noise-equivalent passbands.

The layer thickness in rotational panoramic radiography is presented with the use of the concept of the noise-equivalent passband. Conventionally, the layer thickness has been calculated only from one-dimensional data in the horizontal or rotational dimension of panoramic radiography. In the present study, results from calculations using both one- and two-dimensional data are presented. When the vertical dimension is included in the calculations, the layer is wider than when calculated from data in the horizontal dimension only. It is pointed out that the wider layer that follows from the introduction of the vertical dimension may be the most reliable measure of layer thickness in panoramic radiography.

Bone Density↗
PubMed1993

Increased plasma endothelin-1 concentrations in E. coli septic peritonitis rats with diabetes mellitus.

To study the diabetic mellitus (DM) patient's reaction to sepsis, we investigated the survival rate, the bacteremia, plasma endotoxin and plasma endothelin-1 levels in E. coli septic peritonitis rats with or without streptozotocin-induced DM. No significant difference could be detected between the DM and nondiabetic rats in the survival rate, the bacteremia level or the plasma endotoxin level. The DM rat manifested a significant increase compared to the nondiabetic rat in the plasma endothelin-1 level four hours after the outbreak of peritonitis. Endothelin-1 may thus play some role in the E. coli septic peritonitis rat with DM.

Animals↗
PubMed1993

Concentrations of cytokines in peritoneal fluid after abdominal surgery.

OBJECTIVE: To assess the role of concentrations of cytokines in peritoneal fluid in estimating the severity of the host's response to the stress of abdominal operations. DESIGN: Prospective study. SETTING: University hospital, Japan. SUBJECT: 49 patients who underwent various abdominal operations. Main outcome measures--Correlations between concentrations of tumor necrosis factor-alpha (TNF-alpha), interleukin-1 beta (IL-1 beta), and interleukin-6 (IL-6) in peritoneal fluid measured on the first postoperative day on the one hand, and peritoneal bacterial count, length of operation, and operative blood loss, on the other. RESULTS: The concentrations of all three peritoneal cytokines correlated significantly with length of operation; those of TNF-alpha and IL-1 beta also correlated significantly with peritoneal bacterial count, and that of IL-1 beta with operative blood loss. There were significant correlations between the concentrations of the three cytokines. CONCLUSION: These correlations suggest that monitoring of the peritoneal concentrations of TNF-alpha, IL-1 beta, and IL-6 may be helpful in estimating the severity of stress caused by abdominal operations.

Abdomen↗
PubMed1993

Mortality rate and bacteremia, endotoxin, and endothelin-1 levels in antibiotic therapy for E. coli septic peritonitis.

In order to study the mortality rate and bacteremia, plasma endotoxin, and plasma endothelin-1 levels in antibiotic therapy for E. coli peritonitis, blood samples were obtained from rats given intraperitoneal injections of latamoxef or placebo. Intraperitoneal injections of latamoxef improved the prognosis of peritonitis rats. Two h after treatment, bacteremia levels were noticeably higher in rats treated with placebo than in rats treated with latamoxef, but the latamoxef-treated group manifested a significant elevation of plasma endotoxin and endothelin-1 levels compared to the placebo-treated group. The results of this study demonstrate that treating E. coli septic peritonitis with selected antibiotics induces increased plasma endotoxin levels, which are associated with elevation of plasma endothelin-1 levels.

Animals↗