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M Sigiel

Publications and source records attributed to M Sigiel.

18 recordsLinked to original sources
PubMed1976

Cavum veli interpositi. Roentgen anatomy - pathology and physiology.

158 pneumoencephalographies of infants less than 2 years old were examined and 53 of them had a large cavum veli interpositi. A neuroradiological description of this cistern is given and a comparison made with injected anatomical specimens. A statistical comparison with 105 pneumoencephalographies without a cavum veli interpositi does not shown any correlation between the presence of this cistern and pathological conditions. This investigation indicates that a large cavum veli interpositi in the newborn has no relation to hydrocephalus or cerebral atrophy. The younger the child, the more frequent is the presence of this cistern, especially under eight months of age.

Brain↗
PubMed1976

[Various risk factors in the precipitaiton of complications caused by anesthetics and muscle relaxants].

From this study an important notion emerges concerning the risk factors in accidents due to general anaesthetics and myorelaxants. Among these factors, three are clinical parameters which can be assessed by any anaesthetist: the presence of atopy, of a previous drug allergy, of previous, repeated general anaesthesia, close together in timel Two factors were the subject of an experimental study, routinely investigating an abnormal histamine reactivity of the skin, and a latent spasmophilia. No definite conclusion can be made from the results, bearing in mind certain criticisms of technical order and the small number of subjects investigated. However, these works merit being pursued. Thus, if all subjects are not equal when faced with the risks inherent to anaesthesia, a thorough study of individual risk factors will enable a preventive approach, utilising a premedication prescribed with mature consideration.

Anaphylaxis↗
PubMed1976

[In vivo blood histamine during anesthesia].

Assays of overal histaminaemia were carried out, in 150 patients anaesthetised according to three different techniques, apart from any surgical act. 119 anaesthesias took place without any incident, 33 were disturbed by the appearance of rashes or of bronchospasm. The overall histaminaemia varied according to three types of graphs (a flat graph, an ascending graph, or a descending graph) without it being possible to evoke any relationship between this course and the clinical signs. It seems that the presence of a background predisposing to histamine-liberation is however responsible for greater frequency of the descending graphs, and that the method of administration of the anaesthetic product is a factor which can intervene in the genesis of the phenomena of histamine-liberation during anaesthesia. An interpretation of the variations in the graphs of histaminaemia is attempted by the authors.

Adolescent↗
PubMed1976

[Anaphylactoid complications due to the use of anesthetic products and adjuvants. Apropos of 18 cases].

Eighteen grave anaphylactic accidents arising during induction or during anaesthesia, are analysed. By order of frequency, the clinical signs are cutaneous manifestations (70 p. 100 of the cases), bronchospasm (65 p. 100), cardiovascular collapse (45 p. 100). In four cases, cardiac arrest occurred. The course was always favourable, with no after-effects. Immuno-allergic tests enabled one to make the diagnosis of true anaphylaxis in eight cases (seven shocks due to succinylcholine, one due to propanidide), of non specific histamine-liberation in five cases; in the other cases, it was impossible to express an opinion.

Adjuvants, Pharmaceutic↗
PubMed1975

[Effects of Alfatesin on total cerebral blood flow in humans].

The total cerebral blood flow was measured by the Xe 133 in 9 patients, before and during a pure Alfatesine induced anaesthesia. With a perfusion flow of 0,04 ml/kg/mn, the total flow underwent a mean fall of 38 p. 100 that was linked neither to any systemic pressure variations nor to variations of the PaCO2. This fall was linked to a cerebral arterio vasoconstriction as it was evidenced by arteriographic images.

Adolescent↗
PubMedDate not supplied

[Embolization in the jugulo-tympanic chemodectoma. Value, indications and results].

Jugulo-tympanic chemodectomas are usually treated by means of surgical ablation and radiotherapy, these two techniques being used either in isolation or association. The recent advent of embolization, which has undergone considerable development in the field of vasular neuro-radiology within the last few years, open up new therapeutic possibilities for these vascular tumours. A study of three personal cases, followed up after a substantial lapse of time, gives a good idea of the importance of embolization in the therapeutic armoury. In fact, although embolization used alone can cause a reduction in functional symptomatology and even and objective clinical improvement (disappearance of some lesions of the cranial pairs, for exemple), it is regularly followed by repermeabilization of the various pediculi. Embolization used in isolation should therefore be reserved for patients who are inoperable for reasons for extension or associated deficiencies. Embolization appears to be of value before the operation as it results in less haemorrhage and may also be of value before radiotherapy.

Adult↗
PubMedDate not supplied

[Suxamethonium].

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Animals↗