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Biomedical subjects

M Sims

Publications and source records attributed to M Sims.

29 records · Page 2Linked to original sources
PubMed1980

Obstructing gastric carcinoma complicating pregnancy.

Although gastric cancer has not been reported in association with pregnancy, the authors encountered it in a paraplegic young pregnant woman presenting with gastric outlet obstruction.Fiberoptic gastroscopy and biopsy provided the surprising tissue diagnosis. Ultrasound was helpful in assessing the size and position of the fetus. Intravenous fluid therapy and total parenteral nutrition enabled the authors to correct the negative nitrogen balance and metabolic derangement, and to improve the operative risk to both the mother and the fetus.Cesarean section delivered a viable baby. A high gastrectomy relieved the patient of her obstruction and tumor burden. Although the long-term prognosis of gastric cancer remains grim, having saved the mother and the baby through such an ordeal is a rewarding experience.

Adult↗
PubMed1979

Mastitis-metritis-agalactia complex in sows: effect of the dosage of oxytocin on intramammary pressure in lactating healthy sows.

The dose-response and time-response relationships between injected oxytocin and intramammary pressure were investigated in normal lactating sows. In less than 39 s after 20, 40, or 80 U of oxytocin was given (IM injection), there was a rapid initial increase in intramammary pressure (15 to 27 mm of Hg) which lasted 22 to 32 s. After this initial response, there were secondary oscillations in pressure which lasted approximately 40 minutes (20 U) and up to 60 minutes (40 or 80 U). Changes in intramammary pressure during each oscillation varied between 1 and 5 mm of Hg. Mean values for frequency and amplitude of oscillations and total work (area under the trace) were measured. Compared with response obtained after 20 U of oxytocin was given, responses obtained at the 40-U or 80-U dose level had an increased frequency (150.0% and 249.0%, respectively) and total work (36.6% and 104.4%, respectively), but not amplitude. Thus, there may be some clinical advantage in milk let-down effect when sows are given the larger doses of oxytocin (40 or 80 U). These results indicate that newborn pigs should be allowed to nurse at the same time in which oxytocin is injected.

Animals↗
PubMedDate not supplied

Evaluation of progress using the context input process and product model.

Most evaluations of programme effectiveness are based on process data (the data generated by the programme) and used for internal monitoring and service development. Context (the ecology of therapeutic systems), input (the identification of what is in fact different between two therapeutic systems) and product (the consequence of different inputs, taking account of context) evaluations are rarely, if ever, produced. In this paper (using input and product evaluations) the progress of twelve Down's syndrome and twelve multiply-handicapped children attending, over a period of 18 months, two different therapeutic systems operated by the New Zealand Society for the Intellectually Handicapped (Auckland Branch/outside Auckland Branches) is assessed. The progress of the Auckland children is significantly better in a number of areas than for those outside Auckland. This improvement in progress can be attributed to input differences that reflect the Auckland Branch's policy of service development. The most important determinants of a successful programme are not staff/student ratios, time in class or specialist assistance, all of which favour the outside Auckland groups, but the degree of structure, detail of programmes and assessments, and quality of parent contact in which Auckland seems superior. The results for the Down's syndrome group compare favourably with those from other Down's syndrome programmes.

Activities of Daily Living↗
PubMedDate not supplied

Duane's retraction syndrome associated with optic nerve hypoplasia.

A patient with unilateral Duane's retraction syndrome and optic nerve hypoplasia is presented. The occurrence of these anomalies not previously reported together in a patient, supports the hypothesis of a disturbance in embryogenesis during the second gestational month as the etiology of the retraction syndrome.

Child, Preschool↗