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Biomedical subjects

M Slim

Publications and source records attributed to M Slim.

29 records · Page 2Linked to original sources

Congenital choledochal cysts.

Cystic dilation of the common bile duct is a rare congenital anomaly. The cases of two patients, 2 1/2 and 18 years old, respectively, illustrate the difficulty in preoperative diagnosis, as well as the value of long-term postoperative follow-up. Ascending cholangitis developed in one of the patients after a Roux-en-Y cystojejunostomy nine years after operation. A follow-up of three years after cystoduodenostomy and 14 years after a hepaticojejunostomy is reported. In infants and small children, a cystoduodenostomy is usually done; otherwise, cystojejunostomy should be the preferred initial operation. Excision may be attempted if the cyst is very small, and in selected cases.

Adolescent↗

Pyloro-duodenal atresia. A report of three families with several similarly affected children.

Seven patients born with pyloro-duodenal atresia are reported, one had an additional atresia of the small and large bowel, and another had a pneumoperitoneum probably secondary to rupture of the stomach. All patients had the same radiological findings and had no air distal to the pylorus. Consanguinity was elicited in four and a familial incidence of an identical malformation in siblings in six. 6 of the 7 patients were operated on and 4 are living and well 6 months to 5 years later. This report raises the total number of published cases of pyloro-duodenal atresia to 46, and provides further evidence for an autosomal recessive mode of inheritance.

Duodenum↗

Solid variant of aneurysmal bone cyst in a patient with cyclic neutropenia.

A 16-year-old female with cyclic neutropenia (CN) was incidentally found to have a thoracic vertebral mass during the preoperative work-up for maxillary sinus surgery. An exploratory thoracotomy revealed a very vascular tumor involving T-10 and T-11 vertebral bodies. Gross total resection of the tumor was achieved. Pathology revealed a solid variant of aneurysmal bone cyst. This is a rare benign neoplasm of bone more commonly seen in the mandible and facial bones as well as involving the small tubular bones of the hands and feet. Because of its rarity, location, and an unknown association with CN, we found this case worthwhile to publish.

Adolescent↗

Thrombosed Björk-Shiley standard disc mitral valve prosthesis.

Between April 1980 and June 1986, 274 patients underwent mitral valve replacement (MVR) with the Björk-Shiley (BS) standard disc mitral valve prosthesis at the American University of Beirut Medical Center (AUBMC). Eleven patients (3.9%) presented 6-41 months after surgery with prosthetic valve dysfunction due to thrombosis. Inadequate control of anticoagulation was the major factor predisposing to thrombosis in all except one. All patients had documented rheumatic valvular disease. Nine patients were operated on an emergency basis and two died before any surgical intervention was possible. Thrombectomy was performed on six patients with four survivors and MVR in three with two survivors. Two patients died intraoperatively (22%). Three pregnant patients underwent mechanical declotting; pregnancy was terminated by abortion in 2 and by caesarean section and live birth in one. We conclude that implantation of the BS mitral valve prosthesis mandates emphasis on anticoagulation and the difficulty encountered with continuous anticoagulant therapy in pregnancy.

Adolescent↗

Injuries to vessels of neck.

A personal experience at the American University Medical Center with vascular neck injuries occurring between May and December 1976 is reported. Five unusual cases are presented and discussed, their ages ranging between 10 and 25 years. The causative agent was shrapnel in four and bullet in one. Four of the five cases had multiple associated injuries. The vessels involved were the carotid artery with internal jugular vein in two cases, the subclavian vein in one, the superior thyroid artery in one, and the carotid and vertebral arteries in one. The treatment consisted of a combined cervico-thoracic approach in two cases, a claviculectomy in one, suture-ligation and aneurysmectomy in four and venous graft to the artery in one. The complications consisted of postoperative bleeding in one case, partial facial nerve paresis in another, and superficial wound infection in a third. No deaths occurred among the five complicated cases presented.

Adolescent↗

Penetrating injuries of the heart and the great vessels.

Twenty eight patients with penetrating injuries to the heart and/or the great vessels are presented. These constituted 9% of all penetrating chest injuries during the period between April 1975 and November 1976. The injuries were confined to the cardio-vascular system in 3 patients only. Twelve patients presented with signs of cardiac tamponade, of whom 2 succumbed intra-operatively due to ventricular fibrillation. Eight patients required respiratory support immediately after operation, of whom one died eventually due to extra-cardiac injuries. The mortality rate in this series was 11%. The remaining 25 survivors have resumed their regular life activities after discharge from the hospital. In none of the cases was the heart-lung machine used for repair.

Adolescent↗