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Biomedical subjects

M Sośnierz

Publications and source records attributed to M Sośnierz.

At least 19 recordsLinked to original sources
PubMed1977

[Morphological changes in rats during short-term chronic poisoning with Karbafos].

The animals were exposed to the shortened chronic poisoning with "Karbafos" in doses 20, 70, 250, and 850 ppm adminstered in fodder during 13 weeks. After the end of experiment, the animals were killed and their organs weighed. In the collected specimens, prepared histologically, were found the increase of the kidney mass and many nonspecific pathomorphotic changes. The pulmonary edema, parenchymatous degeneration in heart, kidneys and liver are--according to the authors--directly connected with "Karbafos" action. The intensification of changes was bound with the size of applied dose of preparation. The investigations allowed to fix the highest tolerance dose of "Karbafos" amounting to 20 ppm.

Animals↗
PubMed1976

Influence of estrogens on intraocular tension in the eyeballs of rabbits.

Iridocorneal angles from the eyes of female rabbits subjected to large doses of estrogens were examined under an electron scanning microscope. A temporary rise in intraocular tension was noted lasting up to 24 h after injection of estrogens, followed by a slow return to normal conditions. Histostructural changes of the iridicorneal angle were observed as widening of the marginal sector, enlarging of the dimple-shaped depressions and also increased number and narrowing of the micropores in the central part of the iridocorneal field. The authors postulate that estrogens affect the histostructure of the iridocorneal field and also stimulate the circulation of the aqueous fluid.

Animals↗