[A case of myositis ossificans of fibrodysplasia ossificans progressiva type].
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Child↗
Biomedical subjects
M Somoza
Publications and source records attributed to M Somoza.
[Evaluation of analgesic effects of a compound on a base of acetaminophen, propoxyphene, hydroxyzine and caffein in various dental surgical procedures].
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Adolescent↗
[Electrophysiology in neuropathy caused by vincristine].
Ten patients treated with vincristine were submitted for electrophysiological examination. It was investigated the number of motor units within the thenar muscle following a technique described previously (Sica et al. - 1974); motor and sensitive conduction velocities as well as motor distal latencies in the median nerve were studied following conventional techniques. The behaviour of the evoked muscle potential with repetitive supramaximal stimulation over the median nerve was also investigated. The findings were compared with control groups. The estimated number of motor units was disminished in eight of ten patients and the average number was significantly different from the control group (control 318 +/- 71 UM; patients 174 +/- 84 UM; P less than 0.001). The potential amplitudes in most of the surviving units were reduced, others remaining within the normal range. This makes apparent that the peripherical nervous system fails to compensate adequately and, furthermore, a loss of individual muscle fibres occurs within some individual units. The conduction velocities of the fastest conducting motor nerve fibres were reduced and motor distal latencies prolongued (Table 1). Maximal impulse conduction velocities were measured in sensory fibres. In 5 of 7 subjets investigated the values laied just beyond the lower limit of the normal range. The amplitude of the sensory orthodromic evoked potential in the median nerve at the wrist was disminished almost in the whole group. The decremental muscle response to repetitive nerve stimulation, can be interpreted as the result of the damage at the neural apparatus at the motor end plate; it was observed in 57% of the patients. In summary, evidences have been registered showing that the nervous supply to the muscle is affected in patients treated with vincristine; the motor unit behaviour under this conditions is discussed.
Adult↗
A computerized system for learned helplessness experiments.
A microcomputer-based system for carrying out learned helplessness experiments is described. The hardware is inexpensive and easily available. The program is written in BASIC and must be executed in the compiled form in order to keep up with real-time events. It contains an algorithm for calculating inter-trial intervals and allows the experimentor to freely select experimental conditions such as duration of shock, number of trials, etc. The task that the rat is required to do to stop the shock is also selectable, thus giving the experimentor the opportunity to maximize behavioral differences between escapable and inescapable rats while these differences are being induced. Experimental data on 12 rats that went through this automated protocol are analyzed and discussed.
Analysis of Variance↗