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Biomedical subjects

M Soumare

Publications and source records attributed to M Soumare.

23 records · Page 2Linked to original sources

Twelve-year follow-up study of hepatitis B immunization of Senegalese infants.

Numerous studies have documented the efficacy and safety of plasma-derived and recombinant hepatitis B vaccines. However, little is known about the long-term protection of hepatitis B vaccine, when anti-HBs declines to low or undetectable levels. This study reports results from a 9-12-year period follow up of infants immunized against hepatitis B in Senegal. At the end of the follow-up period anti-HBs were detected in 81% of children who received a booster dose at school age and in 68% of those who did not. HBsAg was detected in 19% of infants from the control group compared to only 2% of immunized infants, corresponding to a protective efficacy of 88%. The results show that long-term protection against HBsAg carriage of hepatitis B vaccination is very high and that a booster dose at school age does not significantly increase this protection.

Child↗

[Seroprevalence of anti-Delta antibodies in hospital workers in Dakar].

708 hospital workers in CHU of Dakar were tested to HBs antigen: among them 128 were positive and tested to Delta antibody by ELISA Abbott kit. Seven men and one woman were positive; however the positivity to Delta antibody is neither linked to sex, nor to age. 87% of the Delta antibody carriers were found among the trainees, and 50% of them studied in the Odonto-Stomatology Institute.

Adolescent↗

[Tetanus after intramuscular injection in an infectious disease service in Dakar. 12-year review (1978-1989)].

Tetanus is a serious toxic-infection common to men and animals produced by a strict anaerobic bacillus: Clostridium Tetani or Nicolaier's Bacillus. It is an infectious, non-contagious, non-immunizing illness, which must be officially notified. Although Tetanus has been known from antiquity and a very efficient specific vaccine is available, in developing countries its frequency and high mortality make it a major problem for Public Health authorities. This dramatic situation in underdeveloped countries is due to: inadequate vaccination and health education; poor infrastructure in health services; the persistence of harmful traditional practices; and disregard for elementary principles of antiseptics and sterilization, leading to the terrible form of tetanus after-muscular injection, a real "tragedy" according to Bourgeade. The aim of this study is to draw attention to the frequency, seriousness and hopeless prognostic of this type of tetanus, all of which could be avoided if simple, elementary, prophylactic measures, such as rigorous disinfection and adequate sterilization of equipment, were undertaken.

Adolescent↗

[Prevalence of Delta hepatitis in health workers in Dakar (Senegal)].

708 hospital workers in University Teaching Hospital of Dakar were tested to HBs antigen; among them 128 were positive and tested to Delta antibody, by ELISA Abbott kit. Seven (7) men and one woman were positive. However, the positivity of Delta antibody is neither linked to sex, nor to age of subjects. 87% of the Delta antibody carriers were found among the trainees, and 50% of them studied in the Odonto-Stomatology Institute.

Enzyme-Linked Immunosorbent Assay↗