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Biomedical subjects

M Spannagel

Publications and source records attributed to M Spannagel.

2 recordsLinked to original sources

[Obstetrical management in dysfibrinogenemia].

Dysfibrinogenaemia is an inherited disorder, characterised by a plasmafibrinogen in normal concentration, but of abnormal quality due to impaired release of fibrinopeptides and/or impaired aggregation of fibrinomonomers. The typical abnormalities of the laboratory findings will be demonstrated by presenting the case reports of 4 patients with 5 pregnancies (1 ectopic pregnancy); the importance of clinical exploration is emphasized. Newborn infants must be subjected to careful clinical and biochemical examination, because of factors of Mendelian dominant inheritance.

Adult↗

Diurnal fluctuations of cell kinetic parameters in the epidermis and the sebaceous gland of the hamster ear.

By using the colcemid method, the presence of a diurnal variation for the mitosis index was confirmed, showing a definite minimum during the night in the sebaceous gland of the Syrian hamster ear. Furthermore, the number of all labelled cells and the quotient "single-labelled 14C-cells + double-labelled cells/single-labelled 3H-cells" determined with double-labelling autoradiography ([3H] and [14C]thymidine) seem to be subject to rhythmic fluctuations, although statistical support for this observation is lacking. The parallelism of the rhythmic variations in the epidermis and in the sebaceous glands is striking.

Animals↗