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Biomedical subjects

M Sparmann

Publications and source records attributed to M Sparmann.

11 recordsLinked to original sources
PubMed1992

[Changes in the vascular endothelium after electro- and thermocoagulation].

An experimental study was performed in animals to investigate the effect of various coagulation techniques on the vascular system. Using a microsurgical procedure, the femoral vein of fifteen rabbits was exposed bilaterally and coagulated until the lumen was closed. Electro- and thermocoagulation systems were applied. The light microscopic examination showed endothelial alterations in the course of the vessel. Analyses with the scanning electron microscope were therefore also performed. Extensive endothelial damage could be detected regularly with monopolar currents; the results were not uniform with bipolar applications. The most favorable conditions were found when thermal coagulators had been used. Damage to the parallel arteries was not detectable to a significant degree in these cases. The toxic effect of the energy applied can be morphologically divided into three stages. It should be considered whether extensive endothelial damage leads to the formation of microthrombi and thus causes clinical complications.

Animals↗
PubMed1991

Proto-oncogene expression in cultured synovial fibroblasts of patients with rheumatoid arthritis.

Total RNA was isolated from cultured synovial fibroblasts of nine patients with rheumatoid arthritis and two controls (cruciate ligament ruptures). RNA was dot-blotted and hybridized with nine different, cloned cellular or viral oncogene probes. None of the proto-oncogenes showed a significant difference of expression in cultured fibroblasts from patients with rheumatoid arthritis when compared to the expression of control fibroblasts.

Arthritis, Rheumatoid↗
PubMed1990

[The vascularized pedicled flap of superior gluteal artery to hip bone chip--a new concept in the revascularization of hip necrosis in adults].

The development and introduction of microsurgical technique has made possible completely new concept of revascularisation surgery in femoral head necrosis. The bone graft described in this presentation is a pedicled one from the lateral ilium. In five femoral head necrosis a pedicled corticocancellous pelvic graft, supplied by the deep branch of the superior gluteal artery, was transplanted in the femoral head. In all cases it was possible to lift out the pelvic graft from the same side as the affected hip joint. Contrary to the medial iliac bone graft (deep circumflex iliac artery) the lateral iliac bone graft (deep branch of the superior gluteal artery) is inserted into the femoral head dorsally. Preoperatively and postoperatively performed selective angiographies are necessary and presented. In all cases an unimpeded perfusion could be shown three months postoperatively. Advantages and indications of the pedicled bone graft are discussed.

Adult↗
PubMed1989

Morphometric study of muscle in congenital idiopathic club foot.

In congenital idiopathic club foot gross morphological changes cannot be assessed in muscle tissue by conventional histopathological techniques. Since, however, recent studies have indicated the presence of neuromuscular anomalies with preponderance of Type 1 fibres in this condition, we have performed histochemical, morphometric and electron microscopic examinations in muscle biopsies of 23 patients with congenital idiopathic club foot deformity. The age of the patients varied between 6 weeks and 12 years, respectively. Muscle biopsy was taken mainly from the flexor group of the affected leg(s) during the surgical correction of the anomaly. No gross pathological changes could be found by histochemical analysis. Morphometric study, however, disclosed abnormalities in the composition of the fibre types. The most prominent change was the percentual increase in Type 1 and decrease in Type 2 fibres in almost all the cases. Electron microscopically, only minor fine structural changes could be found. Since these changes could be assessed soon after birth just as in the later course, they cannot be regarded as the consequence of the abnormal position of the leg. More probably, Type 1 fibre predominance is related etiologically to the congenital club foot deformity.

Biopsy↗
PubMed1987

The forearm flap as a free neurovascular flap for treatment of an extensive bone/soft-tissue defect in the calcaneal part of the foot.

A discussion is presented on the case of a 28-year-old motorcyclist who had an accident and got caught in the spoked wheel of her vehicle. The result was an extensive soft-tissue injury of the metatarsus and calcaneal part of the foot, a defect fracture of the calcaneus, an osseous disinsertion of the Achilles tendon, a lateral malleolus Weber type-A fracture, and a fracture of the second metatarsal bone. The primary treatment consisted in extensive débridement of the strongly contaminated soft parts and refixation of the Achilles tendon on the calcaneus with two osteosynthesis screws. The bruised skin flaps remaining were adapted in a tension-free manner. However, this was possible only in a considerable talipes equinus position. In the further course, the patient developed an extensive skin and soft-tissue necrosis over the calcaneal part of the foot. A neurovascularly pedicled forearm flap was freely grafted in order to maintain the load capacity of the calcaneal part of the foot, to prevent osteitis of the calcaneus, to correct the talipes eqinus position, and to achieve a resensibilization in the load zone of the sole. The healing result was good, and it was possible to achieve extensive correction of the talipes equinus position as well as prevention of calcaneus osteitis; the function of the Achilles tendon was also maintained. Moreover, there was satisfactory resensibilization of the calcaneal part of the foot, so that the patient can now walk in ready-made shoes with a fully molded arch support.

Achilles Tendon↗
PubMed1987

[Thermography as an additional study method in the follow-up of reconstructive operations of the hand].

The hand is very accessible to thermography. Disturbed circulation, vascular disease, tissue damage, or other causes of change in thermoproduction lead to deviation from a normal temperature chart. We found a high correlation between thermographic readings and prognosis after replantation. Thermography is, therefore, a method of examination that can be recommended.

Amputation, Traumatic↗
PubMedDate not supplied

[Macroreplantation of the upper extremity. Report of experiences based on 4 cases].

Amputation of an extremity frequently represents a life-threatening injury and is accompanied by volume deficiency shock through loss of blood. The loss of an arm leads to diability and thus impairs the physical and psychic integrity of the person concerned. This contribution presents 4 cases with macroamputation at the upper extremity, 3 of them involving successfully performed reimplantations. After a historic survey, these cases are used as a basis for discussing the establishment of the indication, the procedure, the complications and the results of the reimplantation.

Adult↗
PubMedDate not supplied

[Recent aspects of the biocompatibility of carbon fibers. A histologic and electron microscopy analysis].

Twenty out of 36 patients who had been treated with a carbon fiber syndesmoplasty were followed up 12-19 months after surgery. Reoperation was performed on 11 patients, in 3 cases for removal of the material and in 8 because of persistent pain, although the syndesmoplasties were stable in the majority of cases. Histologic and electron-microscopic study of the explanted ligaments revealed a considerable foreign-body reaction to the carbon fibers and insufficient metaplasia of the allogenic material to connective tissue.

Biocompatible Materials↗