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Biomedical subjects

M Spinner

Publications and source records attributed to M Spinner.

At least 19 recordsLinked to original sources

Age-of-onset classification of conduct disorder: reliability and validity in a prospective cohort study.

OBJECTIVE: To test in a prospective clinical cohort study the reliability and validity of the age-of-onset subtyping of conduct disorder. METHOD: Participants were adolescents referred to psychiatric clinics who met DSM-III-R criteria for conduct disorder by structured diagnostic interview. Age of onset was the reported age of the first conduct disorder symptom. The reliability of age-of-onset report was tested by assessing agreement within informant on interviews 2 to 4 weeks apart. Age-of-onset groups were compared within informant on rates of correlates and symptom and social functioning outcomes over a period of 3 years. RESULTS: The reliability of age-of-onset report was low (kappa of 0.1 and 0.4 by adolescent and parent informant, respectively). Although the early-onset group had elevated rates of attention-deficit/hyperactivity disorder, family disadvantage, and aggressive and nonaggressive antisocial behaviors at inclusion, growth curve analysis showed that age-of-onset subtyping had no predictive validity. CONCLUSIONS: The reliability of ascertainment of age of onset of antisocial behavior requires further study. While age-of-onset subtyping has heuristic value with respect to the study of the causal pathways to conduct disorder, it is premature to use this system in clinic settings.

Adolescent↗

Tardy posterior interosseous nerve palsy due to childhood osteomyelitis: a case report.

A partial posterior interosseous nerve (PIN) paralysis developed in a patient more than 2 decades after having childhood osteomyelitis of the metaphysis of the radius. In previous reports of tardy PIN palsy, the radial head was dislocated (frequently in cases of unrecognized Monteggia fracture-dislocations), causing compression at the arcade of Frohse. In the patient whose case is discussed here, the radial head was located; compression of the PIN at the arcade of Frohse, in combination with traction against inflamed periosteum, likely resulted in the late development of clinical symptoms and signs.

Adult↗

Predicting the one-year course of adolescent major depression.

OBJECTIVE: To identify specific clinical and social functioning variables that predict persistence of major depression over a 1-year period of follow-up. METHOD: The sample consisted of 67 adolescents with major depression, drawn from consecutive referrals to psychiatric clinics in a defined, geographic catchment area. Clinical interviews and questionnaires measuring behaviors, symptoms, and social functioning were administered to both the adolescent and a parent at inception and at follow-up. Discriminant function analyses were used to identify inception variables that predicted clinical course independent of severity of depressive symptoms and global functioning. RESULTS: At 1-year follow-up, major depression remitted in 66% of subjects. Persisters were characterized at inception as older, more likely to have substance use or anxiety disorders, less involved with fathers, and less responsive to mother's discipline compared with remitters. The effect of these prognostic factors was independent of symptom severity and global functioning. CONCLUSION: These variables appear to reflect perpetuating and ameliorating factors influencing the short-term course of major depression. The findings suggest that treatments for adolescent depression that aim to enhance parent-adolescent relationships, and that specifically target coexisting disorders, should be evaluated for effectiveness.

Adolescent↗

Posterior interosseous nerve compression due to an enlarged bicipital bursa confirmed by MRI.

Posterior interosseous nerve compression is a well-described clinical entity with many aetiologies. Fewer than 12 documented cases of the condition due to an enlarged bicipital bursa exist in the literature. We describe a case in which magnetic resonance imaging (MRI) was used in the preoperative assessment of a mass in the proximal forearm with a clinical diagnosis of partial posterior interosseous nerve compression.

Adult↗

Infraclavicular ulnar nerve entrapment due to a chondroepitrochlearis muscle.

The chondroepitrochlearis muscle is an extremely rare muscle, arising from the pectoralis major, crossing over the neurovascular bundle in the axilla and inserting into the brachial fascia and medial epicondyle of the humerus. This paper presents the first known neurological complication due to the chondroepitrochlearis muscle.

Adult↗

Partial median nerve entrapment in the distal arm because of an accessory bicipital aponeurosis.

We present a newly described entrapment of the median nerve caused by compression in the distal arm because of an accessory bicipital aponeurosis. It is characterized by the paresis or paralysis of muscles innervated by the anterior interosseous branch of the median nerve--the flexor pollicis longus, the flexor digitorum profundus, and the pronator quadratus--as well as other more proximal median nerve innervated muscles, namely, the pronator teres and flexor carpi radialis. Sensibility is intact. The site of the Tinel's sign in the distal arm and the clinical appearance of an accessory bicipital aponeurosis help to localize the lesion. Electrodiagnostic studies are also important in establishing the site of the entrapment. The clinical and surgical findings are correlated with the internal topography of the median nerve at its site of compression. It is important to differentiate this syndrome from the classic anterior interosseous syndrome and other nerve entrapments at the elbow and arm. Surgical exploration is indicated if there is no clinical or electromyographic improvement in three to four months after the onset of symptoms.

Adult↗

An anatomic factor significant in transposition of the ulnar nerve.

Anterior subcutaneous or submuscular transposition of the ulnar nerve are recommended treatments for the cubital tunnel syndrome. Commonly encountered findings at submuscular transposition are the presence of a distinct fibrous septum within the main flexor-pronator origin, which arises from the proximal ulna and medial epicondyle and requires release to accomplish the transposition. Cadaver dissections were conducted to study the intermuscular fascial anatomy of the flexor-pronator origin. The surgical findings were confirmed. The fascial structure is the common aponeurosis between the flexor digitorum superficialis of the ring finger and the humeral head of the flexor carpi ulnaris. Failure to release this structure from the proximal ulna caused kinking and tethering of the nerve when transposition was attempted.

Fascia↗

Anatomic variations in the motor and sensory supply of the thumb.

Variations in the motor and sensory nerve supply to the thumb exist despite stereotyped descriptions in modern anatomy texts. A careful dissection of ten specimens under high magnification has been made with special reference to the nature and incidence of anatomic variations. Transligamentous passage of the recurrent motor branch of the median nerve was noted in six dissections; two of these included multiple motor branches to the thenar musculature. The Riche-Cannieu anastamosis was observed in three specimens. Variations in the branch pattern of the median nerve fibers supplying sensation to the thenar eminance and palmar thumb were also noted. No dorsal (superficial radial nerve) to palmar communications were detected, although this pattern has been described clinically. The differences give rise to an element of diagnostic uncertainty in treating the nerve-injured patient; functional deficits and therapeutic consequences are discussed in relation to the authors' observations and a review of the literature.

Humans↗

Recurrent cavernous haemangioma of the extensor tendons of the hand.

Haemangiomas arising from tendons are very uncommon and are not usually considered in the differential diagnosis of lesions of tendons. The following report is of specific interest for it presents a case of recurrent haemangioma of the extensor tendons of the hand which could be excised and the hand reconstructed at the same operative procedure.

Adult↗

Median nerve entrapment syndrome in the proximal forearm.

Median nerve compression in the proximal forearm is relatively uncommon. This study reviews 71 cases over a 20 year period. Of the 71 in this series, 51 were treated surgically. The time of onset to definitive treatment ranged from 6 months to 5 years, with an average of 9 months. The ages of patients varied from 15 to 56 years and there were 13 males and 58 females. Past criteria for making the diagnosis are reviewed and an added series of clinical observations is made, including three definitive stress tests. In all cases surgically treated compression of the median nerve has been found at one of three levels, in the following order of frequency: the pronator teres, the flexor superficialis arch, and the lacertus fibrosus. Follow-up has been from 6 months to 19 years and four cases in the series were considered to be failures.

Adolescent↗