PubMed HealthSearch

Biomedical subjects

M Støckel

Publications and source records attributed to M Støckel.

5 recordsLinked to original sources

Inflatable splints: do they cause tissue ischaemia?

The effect of increasing pneumatic splint pressure on cutaneous oxygen tension measured transcutaneously (TcPO2) was investigated in 12 subjects. The mean initial TcPO2 was 70.6 mmHg. TcPO2 decreased linearly on increasing the pressure within the splint. TcPO2 became zero at a mean splint pressure of 28 mmHg. Second, three accepted methods used by the ambulance crew to assess inflation pressures of the splint were investigated and found to be unreliable. In the light of these findings the risk of ischaemic complications as a result of applying pneumatic splints to a fractured limb is discussed. We advocate a recommended maximum splint pressure of 15 mmHg and that the splint should be manufactured with a security blow-off valve set at 15 mmHg.

Adult

Liver-cell adenoma. Case report.

A young woman taking oral contraceptives presented with acute, severe abdominal pain. A liver-cell adenoma (weight 1.6 kg), with intrahepatic bleeding and necrosis, was enucleated at elective laparotomy. The clinical presentation of liver-cell adenoma, ranging from incidental finding to sudden death, is reviewed and the evidence linking oral contraceptives to the tumour is discussed. Reported cases of symptomatic liver-cell adenoma have numerically declined in the past decade. Acute surgical treatment is indicated only to control bleeding. In addition to withdrawal of oral contraceptive medication, enucleation of the tumour or hepatic resection is generally recommended as elective, definitive treatment.

Adult

Estimation of 131I-hippuran blood activity from externally registered activity.

The application of data-processing methods such as deconvolution or computer-assisted background subtraction to renography requires knowledge of the input to the kidneys. The two most commonly used approximations to the kidney input in 131I-hippuran probe renography are to assume that the kidney input is described either by the time-activity curve recorded over the subclavian region (mode I) or by the time derivative of mode I (mode II). A third approximation to the kidney input using two externally recorded time-activity curves, pre-injection of 131I-albumin and two venous samples has previously been described. This approach has been modified in this work, in which two externally recorded time-activity curves and two capillary samples are used to construct an estimate for the kidney input (mode III). The three modes are compared with a reference, which is constructed from capillary samples drawn during the renography examination. Eleven patients participated in this study, all of whom were referred for routine renography. The results show that only mode III is close to the reference in all cases.

Adult

The effect of a corticosteroid on the absorption of 131I-albumin from rabbit knee joint.

The disappearance rate of 131I-albumin from the knee joint in six rabbits was measured before and after intraarticular injection of 7.5 mg triamcinolonhexacetonide (Lederspan). A significant decrease in the synovial permeability was demonstrated after injection of triamcinolonhexacetonide (average 64 percent). It is concluded that this demonstrates that corticosteroids have a direct effect on the synovial membrane, which may be an important mechanism whereby they exert their therapeutic effect upon joints.

Animals