[Severe enteritis in newborn and older infants].
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Biomedical subjects
Publications and source records attributed to M Stănescu.
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The authors followed the efficiency of product Macronil in association with the usual (antibiotic and symptomatic) treatments in acute, viral respiratory infections in 62 children, 0-5 years old, admitted into hospital. Besides the usual treatment (25 cases--control group) Macronil was administered in 37 cases (experimental group). A significant improvement was found in clinical evolution (duration of disease evolution, improvement of general state, good appetite, fever duration, increase in weight) of the experimental group versus the control group. An important reduction (twice) of the pharyngeal viral population appeared in the experimental group treated with Macronil. In the control group, the viral flora, remained, practically, the same after treatment.
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Macronil (a concentrated proteic extract from mackerel) associated to usual therapeutics (antibiotics, antipyretics, vitamins) in children aged 0-5 years, with acute respiratory infections led to a reduction of the viral pharyngeal population as detected by immunofluorescence (IF) technics. The IF positivity rate in children receiving Macronil was half as high as in controls receiving only the usual therapeutics. At the same time, the number of virus species detected in the pharynx of Macronil treated children was lower than in controls in which the viral pharyngeal population was not influenced in any way by the administered therapeutics without Macronil.