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Biomedical subjects

M Stanová

Publications and source records attributed to M Stanová.

18 recordsLinked to original sources
PubMed1990

[Malignant atrophic papulosis (Degos' syndrome)].

In a 49-year-old female patient with an eruption of lentil-shaped papules on the trunk and extremities, persisting for six years, originally in another department scleroderma guttata was diagnosed. For one year the patient suffered also from dyspeptic complaints, loss of weight and relapsing polyserositis. The complaints receded temporarily after immunosuppressive therapy. On surgical revision of the abdominal cavity on account of serous peritonitis during the last three months eruption of whitish foci on the intestinal serosa and omentum was found. Bioptic excision of the skin revealed an old bland infarct. From the clinical course and dermatological picture papulosis maligna atrophicans (Degos' syndrome) was diagnosed. Autoptic examination confirmed the clinical diagnosis of the syndrome by the finding of thromangiitis of Bürger's type with bland infarcts of the small intestine and perforation of the jejunum.

Atrophy↗
PubMed1984

The growth of lymphocyte colonies from peripheral blood of patients with malignant melanoma.

Lymphocytes from the peripheral blood of patients with malignant melanoma were cultivated using a modification of the two-layered cultivation method in a semisolid medium. The ability of the cultivated lymphocytes to form colonies and clusters in agar after stimulation with phytohemagglutinin was compared with the actual clinical state of patients. In patients with malignant melanoma, who show clinical signs of progress, significantly less colonies and clusters are formed than in controls. The number of colonies appears to be a more sensitive sign than the number of clusters. For orientation in clinical practice the number of large colonies is of an importance.

Cells, Cultured↗
PubMed1980

[Lamellae annulatae and cisternae radiatae in human tumor cells].

According to a literary survey supplemented with the authors' own observation, lamellae annulatae have already been referred to in a variety of 23 human tumours. Cisternae radiatae, more complicated than lamellae annulatae, have had two literary references; the present authors have found them in three cases: in malignant melanoma, in mammary gland carcinoma, and in pulmonary adenocarcinoma. A new interpretation of the structure of cisternae has been developed, based on three-dimensional projection of pores.

Endoplasmic Reticulum↗
PubMed1978

[Histological, electron-optical and histochemical findings in mycosis fungoides].

Skin excisions were investigated in 5 patients with verified mycosis fungoides. Findings yielded by light and electron microscopy helped to confirm the findings anticipated, and were correlated with histochemical observations. One of the cases involved a substantially higher activity of lysosomal enzymes, particularly KF and beta-glucuronidase in the skin infiltrate mycotic cells. In the other cases, this sort of activity was low. The significance of high ATPase activity in the peripheral cell membrane remains unclear. In one case, involvement in the T lymphocyte series was confirmed by the formation of rosettes.

Aged↗
PubMed1976

[Epithelial tumor-like changes, precancerous conditions and skin neoplasms (standardization study)].

A retrospective study of bioptic material was used to design the following outline of a histological classification of epithelial skin tumours tentatively compared with handbooks published by the WHO (1) and AFIP (2): I. Tumour-like changes: 1. senile verruca (mixed, acanthotic, melanoacanthotic, hyperkeratonic, reticular, inverted). 2. Virus verrucosities (v. vulgaris, v. plana, c. accuminatum, molluscom contagiosum). 3. Hamartogenic verrucosities (naevus verrucosus, n. comedonicus, fibroepithelial papilloma. 4. Genetically undefined verrucosities (acanthosis nigricans, light cell acanthoma, verrucous dyskeratosis). 5. Cysts (atheroma, epidermoid cyst, dermoid cyst, others). 6. Unclassified. II. Precanceroses: 1. Pseudoepitheliomatous hyperplasis, 2. keratosis senilis, 3. Radiation dermatosis, 4. Unclassified. III. Epithelial tumours A. From surface epithelium 1. Spinocellular carcinoma (basic type, anaplastic, adenoid, sarcomatoid, clear cell carcinoma, intraepidermal). 2. Basocellular carcinoma: a) varieties derived from surface epithelium (intraepithelial, superficial, solid, cystic, invasive), b) varieties with adenoid features (cylindromatous, fibroepithelia), c) varieties with trichoepithelial features (keratinizing, pigment-type, clear cell type), d) naevus varieties (basocellular naevi). 3. Spinobasocellular carcinoma. 4. Unclassifiable. B. Sweat gland tumours: 1. syringocystadenoma papilliferum, 2. hidradenoma papillare, 3. nodular hidradenoma (eccrine spiradenoma, eccrine acrospiroma, myxochondroepithelioma, myoepithelioma, mucinous epithelioma), 4. syringoma, 5. eccrine cylindroma, 6. hidrocystoma, 7. eccrine poroma, 8. carcinomas (so called extramammary Paget carcinoma), 9. unclassifiable. C. Sebaceous gland tumours: 1. adenoma sebaceum, 2. carcinoma sebaceum, 3. quasi tumours (naevus sebaceus, Pringle's hamartoma, steatocystoma multiplex, hyperplasia), 4. unclassifiable. D. Trichoepithelial tumours: 1. trichofolliculoma, 2. follicular poroma, 3. keratoacanthoma, 4. tricholemoma, 5. pilomatrixoma, 6. trichogenic adnexal tumour, 7. trichoepithelioma, 8l unclassifiable.

Aging↗