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Biomedical subjects

M Ste-Marie

Publications and source records attributed to M Ste-Marie.

7 recordsLinked to original sources

Symposium on the treatment of inflammatory bowel disease in children and adolescents. Nutritional therapy.

Malnutrition contributes substantially to the severity and morbidity of inflammatory bowel disease in children. Causes of malnutrition include decreased oral intake, excessive nutrient losses, increased nutritional requirements and malabsorption. Nutritional therapy is used to correct specific deficiencies, delayed growth and puberty, and as primary therapy to achieve total bowel rest in patients with disease that is resistant to conventional medical treatment. Total parenteral nutrition has been used successfully in patients with nonfistulous Crohn's disease and in those with retarded growth. Results are not as encouraging in patients who have Crohn's disease with fistula and in patients with ulcerative colitis. Continuous elemental enteral nutrition seems promising, but more controlled studies are needed to assess critically the value of this form of therapy.

Adolescent

Correction of the malabsorption of the preterm infant with a medium-chain triglyceride formula.

After receiving milk-based formula for one week, 16 preterm infants, weighing 1,300 to 1,800 gm, were fed two isocaloric formulas containing either medium-chain or long-chain triglycerides for 15 days; the alternate formula was given for a second period of identical duration. While receiving MCT, the infants had greater (P smaller than 0.01) percent fat absorption (83.4 leads to 97.1%) and weight gain (7.5 leads to 11.5 gm/kg/100 calories). Because metabolic acidosis occurred with the LCT formula, the chloride content was adjusted to that of the MCT were confirmed and, in addition, there was a higher (P smaller than .01) percent retention of nitrogen (67.3 leads to 82.1).

Body Weight

Standardization of cardiopulmonary roentgenograms in infants and children.

Methods were devised to standardize cardiopulmonary radiographs of infants and children. With these techniques, films can be taken either at the end of inspiration and in systole, or at the end of inspiration alone. A statistical evaluation of these two methods demonstrated their superiority over the usual procedure. The use of these techniques is strongly recommended in patients of the pediatric age group.

Adolescent