Biomedical subjects
Publications and source records attributed to M Strange.
The authors present data supporting the conclusion that the transcutaneous bilirubin index may be a valuable tool to help distinguish term babies with a total serum bilirubin value less than 13 mg/dl from those with higher levels and that it serves as a valuable screening device to decrease the number of unnecessary total serum bilirubin tests. Also examined are clinical guidelines and limitations of the device.
A method is described for the detection of trypanosomaemia in mice using the samples of about 55 microliter of blood which can be readily obtained from mice by puncture of the retro-orbital plexus with heparinized glass microhaematocrit tubes. The samples, mixed with an appropriate diluent, are passed through small (2 ml) anion-exchanger columns by means of peristatic pumps and the eluates collected in tubes which can be centrifuged so as to concentrate any organisms in the terminal part of the tube, of calibre about 200 micrometer, for microscopical examination. Evidence is presented to show that the method is more sensitive than other methods in use. It is also quick, requiring only some five minutes per mouse examined.
PURPOSE: This prospective study aimed to evaluate unilateral versus bilateral mandibular nerve block anesthesia with regard to post-operative soft tissue trauma and other complications in a pediatric population. METHODS: A total of 320 patients age 2 to 18 years were appointed for routine operative treatment. There were no age, gender, behavior, or general health exclusions. Oral and written post-operative instructions were given to parents, as well as a survey preview. A phone survey was conducted after treatment to determine a number of variables, including soft tissue trauma. RESULTS: A total of 13% of all patients experienced post-operative soft tissue trauma. By age group, trauma frequency was 18% (< 4 yrs.), 16% (4-7 yrs.), 13% (8-11 yrs.) and 7% (> 12 yrs.). Comparing unilateral versus bilateral subjects as to trauma revealed that in the < 4 age group trauma was higher for the unilateral subjects (35% vs. 5%, P < .02). Non-significant trends showed increased trauma in unilateral groups at ages 8-11 and > 12 years. CONCLUSION: This study represents the first documentation of post-anesthetic soft tissue trauma prevalence in a pediatric population. The results reveal no contraindication to the use of bilateral mandibular block anesthesia.
PURPOSE: The purposes of this investigation were to 1) measure success of a primary tooth pulpotomy technique that applies formocresol in the sub-base without the common five-minute application of a formocresol impregnated cotton pellet; and 2) compare success rates of the pulpotomy procedure using traditional criteria found throughout the literature with new criteria recently established, excluding internal resorption as a radiographic failure. METHODS: Clinical and radiographic data were collected from a retrospective chart review of patients receiving formocresol pulpotomies with the application of formocresol in the zinc oxide-eugenol sub-base. RESULTS: Clinical and radiographic data were available for 196 primary molars in 122 children (followup=six to 103 months; mean=49 months). Traditional assessment of radiographic success and failure yielded a success rate of 79%. Alternative assessment excluding internal resorption as a failure yielded a 99% success rate. Most frequently observed pulpal responses were calcific metamorphosis and internal resorption. Overall clinical success was 99%. Two of the 196 teeth were extracted due to failure. A survival analysis demonstrated that the overall probability of survival remained high over time with a cumulative survival of over 95% after six years. CONCLUSIONS: The overall success rates in this study indicate that the formocresol pulpotomy technique incorporating formocresol in the zinc oxide-eugenol sub-base is a very successful treatment modality for primary molars requiring pulp therapy.