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Biomedical subjects

M Stur

Publications and source records attributed to M Stur.

40 records · Page 3Linked to original sources

[The corneal endothelium--morphology, function and clinical importance].

The corneal endothelium consists of a single layer of flat, hexagonal cells covering the posterior surface of the cornea. It has prominent functions in the maintenance of corneal integrity and transparency. These cells produce Descemet's membrane, dehydrate the corneal stroma, have a barrier function against the aqueous humour and possess active glucose transport mechanisms. Cell density, as well as variation in size and morphology, can be examined by specular microscopy. Pump function and permeability are determined by pachymetry and fluorophotometry. These methods permit early diagnosis of any damage of the corneal endothelium.

Cornea↗

The effect of timolol on the concentrations of albumin and IgG in the aqueous humor of the human eye.

We investigated albumin and IgG concentrations in the aqueous humor of 41 patients before intracapsular cataract extraction (primary samples) and at the end of surgery (secondary samples). Albumin and IgG concentrations were determined in all samples by means of a quantitative fluoroimmunoassay. A short-term topical application of timolol in 24 eyes was associated with a significant increase in both proteins in the primary aqueous humor samples compared with 17 control samples (P less than .005). The ratios of albumin to IgG--even when corrected for serum levels--were not significantly different in the two groups. Timolol did not affect the change in these ratios in the secondary aqueous humor samples. Thus, we concluded that these findings were not caused by a breakdown of the blood-aqueous barrier, but rather resulted from reduced aqueous humor flow and undisturbed protein filtration.

Aged↗

[Cornea pseudoguttata].

Cornea pseudoguttata is the term applied to a temporary, completely reversible lesion of the corneal endothelium during inflammations of the anterior segment of the eye. The posterior specular area of the cornea reveals numerous, partially confluent, dark holes of different sizes. At examination with the specular microscope these holes correspond to intra- and intercellular changes in the endothelial mosaic. It appears that the clinical picture of cornea pseudoguttata is caused by both the edema of the endothelial cells and the looseness of the structure of the endothelial layer due to inter- and subcellular accumulations of fluid.

Corneal Dystrophies, Hereditary↗

[Sectorial racemose vascular malformation of the iris].

A sectorial racemose vascular malformation of the iris in the left eye of a 32-year-old man is reported: a dilated episcleral artery disappeared in the limbal sclera; it reappeared in the chamber angle and after dichotomous branching, continued toward the pupil. The peripupillary capillaries of this sector were dilated, and drained into dilated iris veins.

Adult↗