Epidemiology. Ensuring safe drinking water in Bangladesh.
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Arsenic↗
Biomedical subjects
M Stute
Publications and source records attributed to M Stute.
Global climate models: past, present, and future.
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Journal Article↗
Associations between drinking water and urinary arsenic levels and skin lesions in Bangladesh.
The present study examined the associations between drinking water and urinary arsenic levels and skin lesions among 167 residents of three contiguous villages in Bangladesh. Thirty-six (21.6%) had skin lesions (melanosis, hyperkeratosis, or both), of which 13 (36.1%) occurred in subjects who were currently drinking water containing concentrations of arsenic < 50 micrograms/L. The risk for skin lesions in relation to the exposure estimates based on urinary arsenic was elevated more than 3-fold, with the odds ratios for the highest versus the lowest quartiles being 3.6 (95% confidence interval, 1.2 to 12.1) for urinary total arsenic and 3.2 (95% confidence interval, 1.1 to 10.0) for urinary creatinine-adjusted total arsenic. The risks for skin lesions in relation to the exposure estimates based on arsenic in drinking water were less strongly elevated, with the odds ratios for the highest versus the lowest quartiles of exposure being 1.7 (95% confidence interval, 0.6 to 5.1) for drinking-water arsenic and 2.3 for cumulative arsenic index. The study suggests that arsenic exposure is associated with skin lesions in the Bangladesh population and that urinary arsenic may be a stronger predictor of skin lesions than arsenic in drinking water in this population.
Adult↗
Polygraphic findings in young infants with Joubert's syndrome.
In three young infants with Joubert's syndrome polygraphic recordings were carried out in the awake state and during REM and NREM sleep in order to characterize the respiratory disorder associated with this condition. In all three states disturbed respiration parameters were found in variable amounts. The highest breath rate occurred in the awake state followed by REM and NREM sleep. The highest incidence of apnoea and periodic breathing was observed in NREM sleep, followed by REM sleep and the awake state.
Journal Article↗
[The diameter of the large arteries in the first 3 years of life. An echocardiography study].
The diameters of the great arteries at their origin and also more distal are important parameters for deciding which operation technique should be performed in cyanotic congenital heart diseases. In 130 normal newborn and infants (age between 1 day and 3 years, with a weight of 2,2 through 20 kg) who were examined because of heart murmur diameters of main pulmonary artery, right pulmonary artery, left pulmonary artery, aortic root, ascending aortae, aortic arch, and isthmic region were measured echocardiographically. Then correlations between age and diameters, and weight and diameters were calculated. The mean diameter of ascending aorta grew from 0.84 cm through 1.4 cm, of main pulmonary artery from 0.75 cm through 1.4 cm, of right pulmonary artery from 0.43 cm through 0.86 cm, of left pulmonary artery from 0.42 cm through 0.88 cm, of aortic arch from 0.68 cm through 1.44 cm, and of isthmic region from 0.47 cm through 0.83 cm. The best correlation was found using linear functions between weight and diameters. The "growing-velocity" of ascending aorta was 0.043 cm/1 kg weight gain and 0.05 cm/1 kg weight gain for main pulmonary artery (0.033 cm/1 kg weight gain for right and 0.035 cm/1 kg weight gain for left pulmonary artery). The great arteries grow linearly within the first 3 years of life. The echocardiography was a reliable tool to calculate "growing-velocities".
Aorta↗
Diagnosis, therapy, and outcome of ventricular septal defects in the 1st year of life: a two-dimensional colour-Doppler echocardiography study.
Between January 1987 and July 1989 a ventricular septal defect (VSD) as a single cardiac lesion was detected in 269 small infants aged less than 1 year. The diagnosis was achieved by two-dimensional echocardiography and Doppler colour flow mapping using subcostal, parasternal, apical, and suprasternal views. VSDs were divided into perimembraneous, muscular, malalignment, and subpulmonary defects. Septal defects in complex lesions and atrioventricular defects were excluded. In group 1 (174 infants up to 4 weeks of age, mean 10 days) 125 muscular (71.8%), 35 (20.1%) perimembraneous, 12 (6.9%) malalignment, and 2 (1.1%) subpulmonary defects were diagnosed. One baby had a combined perimembraneous and muscular defect. In another baby a malalignment defect was associated with an av-canal. In group 2 (95 infants aged 4 weeks to 1 year, mean 4.0 months), 57 (60%) muscular, 32 (33.6%) perimembraneous and 6 (6.3%) malalignment defects were found. Within the maximum observation period of 13 months, spontaneous closure occurred in 72 (42.6%) of 169 infants who had a sufficient follow up. Sixty-four had a muscular (88.9%) and 8 (11.1%) a perimembraneous defect. Surgical intervention was required in 11 patients: five perimembraneous defects were closed, one was palliated. Five infants with a malalignment defect were palliated. The malalignment defect frequently needed surgical intervention even in newborns; it never closed spontaneously. About 10% of patients with perimembraneous septal defect required surgery. Spontaneous closure rarely occurred in early infancy. Muscular VSDs were most frequent but virtually never required therapy. Spontaneous closure rate was about 50% during the 1st year of life.
Echocardiography, Doppler↗
[Joubert syndrome combined with unilateral facial paralysis: a rare variant of Joubert syndrome].
We report the case of a mature newborn infant, which aroused attention 8 hours after birth due to an unexplainable paroxysmal tachypnea together with subsequently prolonged apnea. The combination of tachypnea, athetoid movement patterns, apraxia of the tongue, nystagmus and dysplasia of the cerebellum with dilation of the 4th ventricle, led to the diagnosis of Joubert-Syndrome. The child also showed a variation of a connatal unilateral facial nerve palsy, which has not previously been described in connection with a Joubert-Syndrome.
Apnea↗